Velpatasvir D6

Product Name Velpatasvir D6
Alternate Names Velpatasvir Stable Isotopes, Stable Isotopes of Velpatasvir
CAT No. CS-O-16550
CAS No. 1377049-84-7(Unlabeled)
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 889.04 g/mol
Mol. For. C49H48D6N8O8
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Velpatasvir
Purity 95%
Therapeutic Antiretroviral / Anti-HIV
Smileys O=C(N([C@H]1C)[C@@H](CC1)C2=NC3=C(C(C=C(OCC4=CC(C5=CN=C([C@H](C[C@H](COC)C6)N6C([C@@H](C7=CC=CC=C7)NC(OC([2H])([2H])[2H])=O)=O)N5)=CC=C84)C8=C9)=C9C=C3)N2)[C@@H](C(C)C)NC(OC([2H])([2H])[2H])=O
Canonical Smiles CC1CCC(N1C(=O)C(C(C)C)NC(=O)OC)C2=NC3=C(N2)C=CC4=CC5=C(C=C43)OCC6=C5C=CC(=C6)C7=CN=C(N7)C8CC(CN8C(=O)C(C9=CC=CC=C9)NC(=O)OC)COC
InchIKey FHCUMDQMBHQXKK-CDIODLITSA-N
Inchl InChI=1S/C49H54N8O8/c1-26(2)41(54-48(60)63-5)47(59)57-27(3)12-17-38(57)45-51-36-16-14-30-20-35-33-15-13-31(19-32(33)25-65-40(35)21-34(30)43(36)53-45)37-22-50-44(52-37)39-18-28(24-62-4)23-56(39)46(58)42(55-49(61)64-6)29-10-8-7-9-11-29/h7-11,13-16,19-22,26-28,38-39,41-42H,12,17-18,23-25H2,1-6H3,(H,50,52)(H,51,53)(H,54,60)(H,55,61)/t27-,28-,38-,39-,41-,42+/m0/s1
IUPAC methyl N-[(1R)-2-[(2S,4S)-2-[5-[6-[(2S,5S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]-5-methylpyrrolidin-2-yl]-21-oxa-5,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-1(13),2,4(8),5,9,11,14(19),15,17-nonaen-17-yl]-1H-imidazol-2-yl]-4-(methoxymethyl)pyrrolidin-1-yl]-2-oxo-1-phenylethyl]carbamate
Controlled No
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Velpatasvir D6 is a deuterated form of velpatasvir, which is an antiviral medication used in the treatment of chronic hepatitis C virus (HCV) infection. Velpatasvir D6 is a potent inhibitor of the HCV NS5A protein, which plays a crucial role in viral replication and assembly. By inhibiting this protein, velpatasvir D6 prevents the virus from reproducing and spreading, thereby reducing the viral load in the body. Velpatasvir D6 is typically administered as part of a combination therapy with other antiviral drugs such as sofosbuvir and ribavirin. This combination therapy has been found to be highly effective in treating all six genotypes of HCV with minimal side effects. Chemically, velpatasvir D6 is a white to off-white powder with a molecular formula of C49H51D6N8O9S2. It has a molecular weight of 969.18 g/mol, and its chemical structure consists of a pyrrolopyridine core with a fused quinoline ring system. In terms of pharmacokinetics, velpatasvir D6 is rapidly absorbed after oral administration, with peak plasma concentrations reached within 3 to 4 hours. It has a long half-life of approximately 15 hours, allowing for once-daily dosing. Velpatasvir D6 is primarily metabolized in the liver, and its metabolites are excreted in the urine and feces. Overall, velpatasvir D6 is a valuable medication in the treatment of chronic HCV infection, and its chemical properties and pharmacokinetics make it an effective and safe option for patients.

Related Compounds

Velpatasvir-13Cd3 | Velpatasvir 13CD3 | Velpatasvir 13C2 D6 |

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