Lenvatinib D4
| Product Name | Lenvatinib D4 |
|---|---|
| Alternate Names | Lenvatinib Stable Isotopes, Stable Isotopes of Lenvatinib |
| CAT No. | CS-O-16637 |
| CAS No. | 417716-92-8 (Unlabeled) |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 430.88 g/mol |
| Mol. For. | C₂₁H₁₅D₄ClN₄O₄ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Lenvatinib |
| Purity | 95% |
| Therapeutic | Anti-Cancer / Oncology |
| Smileys | ClC1=C(NC(NC2([2H])C([2H])([2H])C2([2H])[2H])=O)C=CC(OC3=CC=NC4=C3C=C(C(N)=O)C(OC)=C4)=C1 |
| Canonical Smiles | COC1=CC2=NC=CC(=C2C=C1C(=O)N)OC3=CC(=C(C=C3)NC(=O)NC4CC4)Cl |
| InchIKey | WOSKHXYHFSIKNG-UHFFFAOYSA-N |
| Inchl | InChI=1S/C21H19ClN4O4/c1-29-19-10-17-13(9-14(19)20(23)27)18(6-7-24-17)30-12-4-5-16(15(22)8-12)26-21(28)25-11-2-3-11/h4-11H,2-3H2,1H3,(H2,23,27)(H2,25,26,28) |
| IUPAC | 4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Lenvatinib D4 is a deuterated version of the drug Lenvatinib, which is used for the treatment of thyroid cancer and renal cell carcinoma. Deuterium is a stable isotope of hydrogen, which has a neutron in its nucleus along with a proton. The substitution of hydrogen with deuterium in the Lenvatinib molecule results in the formation of Lenvatinib D4.
Lenvatinib D4 is used as an internal standard in mass spectrometry analysis of Lenvatinib. It is used to monitor the concentration of Lenvatinib in biological samples, as it reduces the interference from endogenous compounds and improves the accuracy of the analysis. The deuterated version of Lenvatinib also has a longer retention time on the chromatographic column, which enhances the separation of the analyte from other compounds present in the sample.
The chemical structure of Lenvatinib D4 is similar to that of Lenvatinib, with the only difference being the replacement of four hydrogen atoms with deuterium atoms. The molecular weight of Lenvatinib D4 is 426.4 g/mol, and its chemical formula is C21H18D4N4O4. The drug is soluble in dimethyl sulfoxide (DMSO) and ethanol.
In conclusion, Lenvatinib D4 is an important tool for the analysis of Lenvatinib in biological samples. Its stable isotope composition enhances the accuracy and sensitivity of mass spectrometry analysis, which is important for drug development and pharmacokinetic studies.
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Related Compounds
Lenvatinib-15N-d4 | Lenvatinib D5 |