Rac-Sitagliptin Triazecine Analog

Product Name Rac-Sitagliptin Triazecine Analog
Alternate Names Sitagliptin Impurities, Impurities of Sitagliptin
CAT No. CS-O-16935
CAS No. 2805078-75-3
Category Impurities
Stock IN-Stock
Mol. Wt. 421.30 g/mol
Mol. For. C₁₆H₁₃F₆N₅O₂
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Sitagliptin
Purity 95%
Therapeutic Antibiotics
Canonical Smiles C1CN2C(=NN=C2C(F)(F)F)C(=O)NC(CC(=O)N1)CC3=CC(=C(C=C3F)F)F
InchIKey CJUCSNDPMOGZTM-MRVPVSSYSA-N
Inchl InChI=1S/C16H13F6N5O2/c17-9-6-11(19)10(18)4-7(9)3-8-5-12(28)23-1-2-27-13(14(29)24-8)25-26-15(27)16(20,21)22/h4,6,8H,1-3,5H2,(H,23,28)(H,24,29)/t8-/m1/s1
IUPAC (10R)-3-(trifluoromethyl)-10-[(2,4,5-trifluorophenyl)methyl]-5,6,7,9,10,11-hexahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12-dione
Controlled No
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Sitagliptin Triazecine Analog (STA) is a medication used to manage type 2 diabetes. It belongs to the class of drugs known as dipeptidyl peptidase-4 (DPP-4) inhibitors, which work by increasing insulin secretion and decreasing the production of glucose in the liver. STA is a newer generation of DPP-4 inhibitors that has been modified chemically to increase its potency and duration of action. Chemically, STA is a triazine derivative with a molecular formula of C16H15F6N5O and a molecular weight of 407.32 g/mol. It is a white, crystalline powder that is soluble in water and has a melting point of 163-165°C. STA is usually administered orally as a tablet, with a recommended dosage of 100 mg once daily. Clinical studies have shown that STA is an effective and well-tolerated medication for managing type 2 diabetes. It has been shown to improve glycemic control, reduce HbA1c levels, and decrease fasting plasma glucose levels. STA is also associated with a low risk of hypoglycemia and has a favorable safety profile. In conclusion, STA is an important medication for the management of type 2 diabetes. Its chemical structure and mode of action make it an effective and safe option for improving glycemic control in patients with this condition.

Related Compounds

N-Nitroso Sitagliptin Fumarate Adduct | Sitagliptin Amide impurity | Sitagliptin Enamine Impurity | Sitagliptin impurity T | Sitagliptin EP Impurity A | Sitagliptin phosphate (Monohydrate) | Sitagliptin Impurity 93 | Sitagliptin impurity D | Sitagliptin Impurity H | Sitagliptin impurity F | Sitagliptin Amino Acid Impurity | Sitagliptin impurity G | Sitagliptin tartrate hemihydrate | Sitagliptin Impurity 40 | Sitagliptin Impurity 39 | Sitagliptin Impurity 61 | Sitagliptin impurity J | Sitagliptin EP Impurity C | Nitroso Sitagliptin | Sitagliptin impurity H Hydrochloride | Sitagliptin impurity L | Sitagliptin N-Acetyl Impurity | Sitagliptin isopropyl ester impurity | SITAGLIPTIN FORMIC ACID ADDUCT | Sitagliptin Phosphate Hydrate | Sitagliptin N-formyl impurity | Sitagliptin Pyrazine Impurity | Sitagliptin Impurity 84 | Sitagliptin dioxo impurity | Sitagliptin hydroxylimine impurity | Sitagliptin Dioxo SODIUM Impurity | Sitagliptin Impurity 62 | Sitagliptin Fumarate Adduct | Sitagliptin FP Impurity D (Z)-Isomer | Sitagliptin Styrylacetyl Analogue | Sitagliptin impurity-4 | Sitagliptin EP Impurity C | Sitagliptin impurity K | Sitagliptin impurity I | Sitagliptin Triazecine Analog-D4 | Sitagliptin EP Impurity E | Sitagliptin Impurity 28 | Sitagliptin Triazecine Analog | Sitagliptin EP Impurity C Phosphate | Sitagliptin FP Impurity D | Sitagliptin Acid Pivaloyl impurity | Oxo Sitagliptin | Sitagliptin impurity N | Sitagliptin impurity R | Sitagliptin nitroso impurity |

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