Imatinib Dimer
| Product Name | Imatinib Dimer |
|---|---|
| Alternate Names | Imatinib Impurities, Impurities of Imatinib |
| CAT No. | CS-O-20011 |
| CAS No. | 1365802-18-1 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 873.02 g/mol |
| Mol. For. | C₅₂H₄₈N₁₂O₂ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Imatinib |
| Therapeutic | Anti-Cancer / Oncology |
| Smileys | CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)CC4=CC=C(C=C4)C(=O)NC5=CC(=C(C=C5)C)NC6=NC=CC(=N6)C7=CN=CC=C7)NC8=NC=CC(=N8)C9=CN=CC=C9 |
| Canonical Smiles | CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)CC4=CC=C(C=C4)C(=O)NC5=CC(=C(C=C5)C)NC6=NC=CC(=N6)C7=CN=CC=C7)NC8=NC=CC(=N8)C9=CN=CC=C9 |
| InchIKey | DZHKYOWYCVBDPW-UHFFFAOYSA-N |
| Inchl | InChI=1S/C52H48N12O2/c1-35-7-17-43(29-47(35)61-51-55-23-19-45(59-51)41-5-3-21-53-31-41)57-49(65)39-13-9-37(10-14-39)33-63-25-27-64(28-26-63)34-38-11-15-40(16-12-38)50(66)58-44-18-8-36(2)48(30-44)62-52-56-24-20-46(60-52)42-6-4-22-54-32-42/h3-24,29-32H,25-28,33-34H2,1-2H3,(H,57,65)(H,58,66)(H,55,59,61)(H,56,60,62) |
| IUPAC | N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-[[4-[[4-[[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]carbamoyl]phenyl]methyl]piperazin-1-yl]methyl]benzamide |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Imatinib Dimer, also known as N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(4-pyridin-3-yl)pyrimidin-2-ylamino]-2-[(2-hydroxyethyl)carbamoyl]benzamide dimer, is a small molecule drug used in the treatment of chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GIST). It works by inhibiting the activity of tyrosine kinase enzymes, which play a key role in the development of cancer cells.
Imatinib Dimer is typically administered orally in the form of a tablet. The recommended dosage varies based on the patient's weight and other factors, and it is typically taken once or twice daily. Treatment with Imatinib Dimer may continue for several months or years, depending on the patient's response to the drug.
Chemically, Imatinib Dimer is a dimeric form of Imatinib, a tyrosine kinase inhibitor that was first approved by the FDA in 2001. Imatinib Dimer is a white to off-white powder that is soluble in dimethyl sulfoxide, ethanol, and methanol. Its molecular formula is C42H49N11O5 and its molecular weight is 817.9 g/mol.
Like other drugs, Imatinib Dimer may cause side effects. Common side effects include nausea, vomiting, diarrhea, and fatigue. In rare cases, more serious side effects such as liver toxicity and heart problems may occur. Patients taking Imatinib Dimer should be closely monitored by their healthcare provider.
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Related Compounds
Imatinib Impurity 16 | Imatinib EP Impurity D | Des-4-methylpiperazin chloro Imatinib impurity | Imatinib EP Impurity D (chloride) | Fluorescent derivative of imatinib | Imatinib N-Desmethyl Impurity | Imatinib Guanidino Dihydrochloride Impurity | Imatinib N-Formyl Impurity | N-Desmethyl Imatinib Mesylate | Imatinib (Pyridine)-N-oxide | Imatinib Hydrochloride Impurity G | Imatinib Dimethylamino Impurity | Imatinib Impurity 5 | Imatinib DiPiperazine Impurity | Imatinib EP Impurity C Trihydrochloride | Imatinib Imidazole Impurity | Imatinib Impurity 3 | N-Desmethyl -N-Nitroso Imatinib | Imatinib N-Acetyl Impurity | Imatinib (Piperazine)-N4-Oxide | N-Nitroso Imatinib impurity F | N-Desmethyl -n-nitroso imatinib 1 | N-Boc-N-Desmethyl Imatinib | N-(3-methyl5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4((4-methylpiperazin-1-yl)methyl)benz | Imatinib Impurity B | N-Nitroso Imatinib Nitro Intermediate | Imatinib EP Impurity C | Imatinib impurity B | N-Nitroso Imatinib | N-(2-Methyl-5-nitrophenyl)-4-(pyridine-3-yl)pyridine-2-amine | N-Nitroso Imatinib guanidine Intermediate | Imatinib EP Impurity D Tetrahydrochloride | Imatinib (N-nitroso benzamide) |