N-desmethyl netupitant D6

Product Name N-desmethyl netupitant D6
Alternate Names Netupitant Stable Isotopes, Stable Isotopes of Netupitant
CAT No. CS-O-20023
CAS No. 2070015-21-1
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 570.60 g/mol
Mol. For. C₂₉H₂₄D₆F₆N₄₄O
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Netupitant
Purity 99.17
Therapeutic Anti-Cancer / Oncology
Smileys CN(C1=CN=C(N2CCNCC2)C=C1C(C=CC=C3)=C3C)C(C(C([2H])([2H])[2H])(C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)C([2H])([2H])[2H])=O
Controlled No
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N-desmethyl netupitant D6 is a chemical compound that is used in the pharmaceutical industry for its antiemetic properties. It is a deuterated version of N-desmethyl netupitant, which is a selective neurokinin-1 (NK1) receptor antagonist. This means that it blocks the action of the NK1 receptor, which is responsible for transmitting signals of nausea and vomiting in the brain. N-desmethyl netupitant D6 is typically administered as a tablet or capsule and is used to prevent nausea and vomiting associated with chemotherapy, radiation therapy, and surgery. It is also used to treat postoperative nausea and vomiting in adults. The deuterium-labeled version of the compound is used in research studies to better understand its pharmacokinetics and metabolism. Chemically, N-desmethyl netupitant D6 has a molecular formula of C26H17D6F5N3O3 and a molecular weight of 517.54 g/mol. It is a white to off-white powder that is sparingly soluble in water and slightly soluble in ethanol. The compound is stable under normal storage conditions and should be protected from light and moisture. In summary, N-desmethyl netupitant D6 is a valuable antiemetic drug used to prevent nausea and vomiting in cancer patients and those undergoing surgery. Its selective action on the NK1 receptor makes it a highly effective treatment option, and its deuterium-labeled version is used in research studies to better understand its pharmacokinetics and metabolism.

Related Compounds

Netupitant D6 | Monohydroxy Netupitant D6 | Netupitant D8 | Netupitant N-oxide D6 |

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