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Diphenhydramine Impurity K

Also known as: Diphenhydramine Impurities or impurities of Diphenhydramine
Chemical Name Diphenhydramine Impurity K
CAT No. CS-O-30428
CAS Registry# 574-42-5
Status Prompt Dispatch
Category Impurities
Mol. Wt. 350.45 g/mol
Mol. For. C₂₆H₂₂O
Hazardous This is a Hazardous Compound
COA View Sample COA

Additional Information


Controlled No
Parent API Diphenhydramine
Therapeutic Antihistamine
Smileys C1=CC=C(C=C1)C(C2=CC=CC=C2)OC(C3=CC=CC=C3)C4=CC=CC=C4
Canonical Smiles C1=CC=C(C=C1)C(C2=CC=CC=C2)OC(C3=CC=CC=C3)C4=CC=CC=C4
InchIKey PVQATPQSBYNMGE-UHFFFAOYSA-N
Inchl InChI=1S/C26H22O/c1-5-13-21(14-6-1)25(22-15-7-2-8-16-22)27-26(23-17-9-3-10-18-23)24-19-11-4-12-20-24/h1-20,25-26H
IUPAC [benzhydryloxy(phenyl)methyl]benzene
Hazardous Yes


Usage and description


Diphenhydramine Impurity K is a chemical compound that is commonly used as a reference standard or impurity in the analysis of diphenhydramine, an antihistamine drug used to relieve symptoms of allergies, hay fever, and the common cold. This compound is also known as 2-(diphenylmethoxy)-N,N-dimethylethanamine hydrochloride, and its chemical formula is C17H22ClNO. Diphenhydramine Impurity K is a white to off-white crystalline powder that is soluble in water and ethanol. It is typically used in pharmaceutical laboratories to test the purity of diphenhydramine hydrochloride, which is a common active ingredient in many over-the-counter allergy and cold medications. The purity of diphenhydramine hydrochloride is critical to ensure its safety and efficacy in treating allergy symptoms. Diphenhydramine Impurity K is used as a reference standard to measure the purity of diphenhydramine hydrochloride using various analytical techniques such as high-performance liquid chromatography (HPLC), gas chromatography (GC), and mass spectrometry (MS). In conclusion, Diphenhydramine Impurity K is a valuable chemical compound that plays an important role in the analysis and quality control of diphenhydramine hydrochloride. Its high purity and solubility make it an ideal reference standard for analytical laboratories working in the pharmaceutical industry.

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