Sofosbuvir metabolite GS-566500 13CD3

Product Name Sofosbuvir metabolite GS-566500 13CD3
Alternate Names Sofosbuvir Stable Isotopes, Stable Isotopes of Sofosbuvir
CAT No. CS-O-30478
CAS No. 1256490-46-6
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 415.29 g/mol
Mol. For. C12(13C)H16D3FN3O9P
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Sofosbuvir
Purity 97.83
Therapeutic Antiretroviral / Anti-HIV
Smileys F[C@]1([C@H](N(C=CC2=O)C(N2)=O)O[C@H](CO[P](N[C@@H](C)C(O)=O)(O)=O)[C@H]1O)[13C]([2H])([2H])[2H]
Controlled No
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Sofosbuvir metabolite GS-566500 13CD3 is a stable isotopic labeled version of GS-566500, a metabolite of the antiviral drug Sofosbuvir. Sofosbuvir is a direct-acting antiviral medication used in the treatment of chronic hepatitis C virus (HCV) infection. The drug works by inhibiting the HCV RNA polymerase, which is essential for viral replication. GS-566500 is one of the major metabolites of Sofosbuvir, formed by the cytochrome P450 system in the liver. The stable isotopic labeled version of GS-566500, GS-566500 13CD3, is used in pharmacokinetic studies to assess the metabolism and elimination of Sofosbuvir in the body. This is done by administering a dose of Sofosbuvir to a patient and then monitoring the levels of GS-566500 and GS-566500 13CD3 in their blood or urine over time. The use of GS-566500 13CD3 allows for more accurate measurement of Sofosbuvir metabolism and elimination, which can help in determining optimal dosing regimens and predicting potential drug interactions. Chemically, GS-566500 13CD3 is a labeled version of GS-566500, with three deuterium atoms replacing three hydrogen atoms in the molecule. Deuterium is a stable, non-radioactive isotope of hydrogen that has a slightly higher mass, making it useful for tracking the metabolism of drugs in the body. Overall, the use of GS-566500 13CD3 is an important tool in the development and optimization of Sofosbuvir therapy for patients with HCV infection.

Related Compounds

Sofosbuvir Met. D-13C-15N2 | Sofosbuvir D6 | Sofosbuvir metabolite GS331007 13CD3 | Sofosbuvir 13CD3 |

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