Omeprazole Hydrolysis Impurity

Product Name Omeprazole Hydrolysis Impurity
Alternate Names Omeprazole Impurities, Impurities of Omeprazole
CAT No. CS-O-30490
CAS No. 1227380-90-6
Category Impurities
Stock IN-Stock
Mol. Wt. 335.29 g/mol
Mol. For. C₁₆H₁₄N₃NaO₄
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Omeprazole
Purity Not less than 95 %
Therapeutic Anti ulcer
Smileys OC(C(N(C=C(C)C1=O)C2=NC3=CC(OC)=CC=C3N2)=C1C)=O
Canonical Smiles CC1=CN(C(=C(C1=O)C)C(=O)O)C2=NC3=C(N2)C=C(C=C3)OC
InchIKey CDVIAIZPAAQCEE-UHFFFAOYSA-N
Inchl InChI=1S/C16H15N3O4/c1-8-7-19(13(15(21)22)9(2)14(8)20)16-17-11-5-4-10(23-3)6-12(11)18-16/h4-7H,1-3H3,(H,17,18)(H,21,22)
IUPAC 1-(6-methoxy-1H-benzimidazol-2-yl)-3,5-dimethyl-4-oxopyridine-2-carboxylic acid
Controlled No
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Omeprazole Hydrolysis Impurity is a chemical compound that is commonly used in the pharmaceutical industry. It is formed as a by-product during the synthesis of Omeprazole, a proton pump inhibitor used to treat various gastrointestinal disorders like GERD, ulcers, and Zollinger-Ellison syndrome. The compound is a degradation product of Omeprazole and can be found in small amounts in Omeprazole formulations. It is an impurity that can affect the quality, efficacy, and safety of the drug product. Therefore, it is essential to monitor and control its levels during the manufacturing process. Omeprazole Hydrolysis Impurity has a molecular weight of 345.39 g/mol and a chemical formula of C17H18N3O2S. It is a yellowish-brown solid that is slightly soluble in water and soluble in organic solvents like ethanol and methanol. The compound is formed when Omeprazole is exposed to acidic conditions or water, leading to the hydrolysis of the sulfoxide moiety to a sulfone. The impurity can also be formed during the storage of Omeprazole formulations under certain conditions like high temperature and humidity. In conclusion, Omeprazole Hydrolysis Impurity is an impurity that needs to be monitored and controlled during the manufacturing of Omeprazole formulations. Its presence can affect the quality, efficacy, and safety of the drug product.

Related Compounds

Omeprazole sulfide 5-carboxylic acid | Omeprazole Impurity 8 | O,O-Didesmethyl Omeprazole | Omeprazole Impurity 25 | Omeprazole Impurity- K | N-(4-Methoxy-3,5-dimethyl-2-pyridinyl)methyl Omeprazole | Omeprazole Sulfide N1-Methyl 5-Methoxy Analog | Omeprazole Impurity 24 | Omeprazole impurity (DIMER Mixture) | Omeprazole EP impurity B | Omeprazole EP Impurity F | N-Nitroso Omeprazole sodium | Omeprazole impurity D | Omeprazole EP Impurity G | N-Methyl Omeprazole (Mixture of isomers with the methylated nitrogens of imidazole) | Omeprazole EP impurity F & G Mixture | Omeprazole Impurity 79 | Omeprazole Impurity 63 | Desulfoxide 4-Demethyl Omeprazole | Omeprazole  EP Impurity C | Omeprazole Related Compound 5 | Omeprazole Impurity 53 | Omeprazole O-hydrogen sulfite | N-methyl Omeprazole | Omeprazole dibenzimidazole Impurity | o-Toluoyl-5-hydroxy Omeprazole Sulfide | Omeprazole Related Compound 7 | Omeprazole Isomer-2 5-Methoxy -1-[(4-methoxy-3,5-dimethyl-2-pyridinyl)]-0[2-(4-methoxy-3,5-dimethyl -2-pyridinyl)methyl]-sulfanyl]-1H-banzimidole | Omeprazole Impurity 30 | N-Nitroso Omeprazole EP Impurity I | Omeprazole EP impurity I | Omeprazole Acid Methyl Ester Sulfide | N-Nitroso Omeprazole Sulfide | Omeprazole-N-(S)-camphorsulfonamide | N-Methyl Esomeprazole Isomer-1 | Omeprazole Impurity 60 | Omeprazole D13 | Omeprazole EP Impurity A | Omeprazole D15 | Bis-Desmethoxy Omeprazole Sulfide |

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