Isosorbide-2-mononitrate 13C6

Product Name Isosorbide-2-mononitrate 13C6
Alternate Names Isosorbide Stable Isotopes, Stable Isotopes of Isosorbide
CAT No. CS-O-30502
CAS No. 1391051-97-0 (Relative Stereo)
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 197.09 g/mol
Mol. For. ¹³C₆H₉NO₆
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Isosorbide
Purity Not less than 95 %
Smileys O=[N](O[13C@@H]1[13C@](O[13CH2][13C@H]2O)([H])[13C@]2([H])O[13CH2]1)=O
Controlled No
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Isosorbide-2-mononitrate 13C6, also known as ISMN-13C6, is a stable isotope-labeled analog of isosorbide-2-mononitrate (ISMN). ISMN is a medication used to prevent and treat angina pectoris, which is chest pain caused by insufficient blood flow to the heart. ISMN works by dilating the blood vessels, which reduces the workload of the heart and increases blood flow to the heart. ISMN-13C6 is used in pharmacokinetic studies as a tracer to quantify drug metabolism and pharmacokinetics. It is also used in research to investigate the pharmacological effects of ISMN in humans and animals. Chemically, ISMN-13C6 is a nitrate ester of isosorbide, which is a cyclic carbohydrate. It has the molecular formula C6H8N2O8^13C6 and a molecular weight of 260.14 g/mol. It is a white to off-white powder that is stable under normal conditions. The metabolism of ISMN-13C6 is similar to that of ISMN. It is rapidly absorbed in the gastrointestinal tract and undergoes first-pass metabolism in the liver, where it is converted to the active metabolite, isosorbide-5-mononitrate. The half-life of ISMN-13C6 is approximately 5 hours, and it is primarily excreted in the urine. In conclusion, ISMN-13C6 is a useful tool in pharmacokinetic and pharmacological research of ISMN. Its chemical properties and metabolism are similar to ISMN, and it is a safe and stable isotope-labeled analog.

Related Compounds

Isosorbide 13C6 Dinitrate |

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