7-ethyl Camptothecin
| Product Name | 7-ethyl Camptothecin |
|---|---|
| Alternate Names | Camptothecin Impurities, Impurities of Camptothecin |
| CAT No. | CS-O-30626 |
| CAS No. | 78287-27-1 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 376.41 g/mol |
| Mol. For. | C₂₂H₂₀N₂O₄ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Camptothecin |
| Purity | 97.34 |
| Smileys | CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=CC=CC=C51 |
| Canonical Smiles | CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=CC=CC=C51 |
| InchIKey | MYQKIWCVEPUPIL-QFIPXVFZSA-N |
| Inchl | InChI=1S/C22H20N2O4/c1-3-12-13-7-5-6-8-17(13)23-19-14(12)10-24-18(19)9-16-15(20(24)25)11-28-21(26)22(16,27)4-2/h5-9,27H,3-4,10-11H2,1-2H3/t22-/m0/s1 |
| IUPAC | (19S)-10,19-diethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
7-Ethyl Camptothecin is a synthetic analogue of Camptothecin, a natural alkaloid isolated from the bark and stem of Camptotheca acuminata. It is a potent anticancer drug that has shown efficacy against a variety of malignancies, including breast, lung, ovarian, and colon cancers. The anti-tumor activity of 7-Ethyl Camptothecin is due to its ability to inhibit topoisomerase I enzyme, which is essential for DNA replication and cell division. The drug binds to the enzyme-DNA complex, preventing the relaxation of the supercoiled DNA and causing DNA damage that results in cell death.
7-Ethyl Camptothecin is administered intravenously and has a short half-life of approximately 10 minutes. The drug is rapidly cleared from the body and is metabolized in the liver. The recommended dosage of 7-Ethyl Camptothecin varies depending on the type of cancer being treated, the patient's weight and overall health, and other factors.
Like Camptothecin, 7-Ethyl Camptothecin is a highly unstable compound that is sensitive to light, heat, and acidic conditions. The drug must be stored in a cool, dry place and protected from light until it is ready for use. In addition, 7-Ethyl Camptothecin is a potent irritant to the skin and mucous membranes, and precautions should be taken to avoid exposure during handling and administration. Despite these challenges, 7-Ethyl Camptothecin remains an important tool in the fight against cancer and continues to be studied for its potential in combination therapies and targeted drug delivery.
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Related Compounds
Camptothecin Impurity 8 | keto protection of Camptothecin impurity | Camptothecin Impurity D | Camptothecin 7-Ethyl Impurity |