7-Epipaclitaxel
| Product Name | 7-Epipaclitaxel |
|---|---|
| Alternate Names | Paclitaxel Impurities, Impurities of Paclitaxel |
| CAT No. | CS-O-31068 |
| CAS No. | 105454-04-4 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 853.91 g/mol |
| Mol. For. | C₄₇H₅₁NO₁₄ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Paclitaxel |
| Purity | 95% |
| Therapeutic | Anti-Cancer / Oncology |
| Smileys | CC(O[C@@]1([C@](C[C@H]2O)([H])OC1)[C@@]([C@@]2(C3=O)C)([H])[C@@H]([C@@](C4(C)C)(C[C@H](OC([C@H](O)[C@H](C5=CC=CC=C5)NC(C6=CC=CC=C6)=O)=O)C(C)=C4[C@H]3OC(C)=O)O)OC(C7=CC=CC=C7)=O)=O |
| Canonical Smiles | CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C |
| InchIKey | RCINICONZNJXQF-LYTKHFMESA-N |
| Inchl | InChI=1S/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33-46(38,24-58-33)62-27(3)50)39(53)37(59-26(2)49)34(25)44(47,4)5/h7-21,31-33,35-38,40,51-52,57H,22-24H2,1-6H3,(H,48,54)/t31-,32+,33+,35-,36+,37+,38-,40-,45+,46-,47+/m0/s1 |
| IUPAC | [(1S,2S,3R,4S,7R,9R,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
7-Epipaclitaxel is a semi-synthetic derivative of paclitaxel, which is a natural product extracted from the bark of the Pacific yew tree. It is a chemotherapy drug used in the treatment of various types of cancer, including breast cancer, lung cancer, and ovarian cancer. 7-Epipaclitaxel works by preventing the division of cancer cells, thus inhibiting their growth and spreading throughout the body.
The chemical formula of 7-Epipaclitaxel is C47H51NO14, and its molecular weight is 853.91 g/mol. It is a white to pale yellow crystalline powder that is soluble in methanol, ethanol, and dimethyl sulfoxide. The drug is administered through intravenous injection, and the dosage and duration of treatment depend on the type and stage of cancer being treated.
Like paclitaxel, 7-Epipaclitaxel binds to microtubules within cancer cells, stabilizing them and preventing them from breaking down during cell division. This leads to the accumulation of cells in the G2/M phase of the cell cycle, ultimately leading to cell death. However, 7-Epipaclitaxel has been shown to have similar or better antitumor activity than paclitaxel, with fewer side effects, making it a promising alternative for cancer treatment.
In conclusion, 7-Epipaclitaxel is an effective chemotherapy drug used in the treatment of various types of cancer. Its chemical structure and mechanism of action are similar to those of paclitaxel, but it has been shown to have fewer side effects. As such, it is a promising alternative for cancer treatment that warrants further research and development.
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Related Compounds
Paclitaxel Impurity 2 | Paclitaxel photodegradant | Paclitaxel Oxetane Ring-Opened 3-Acetyl 4-Benzoyl Impurity | Paclitaxel EP Impurity I | Paclitaxel C | N-debenzoyl-N-propanoyl-10-deacetyl Paclitaxel | Paclitaxel N-Butyl Analog |