2- Epi Docetaxel
| Product Name | 2- Epi Docetaxel |
|---|---|
| Alternate Names | Docetaxel Impurities, Impurities of Docetaxel |
| CAT No. | CS-O-31077 |
| CAS No. | 133577-33-0 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 807.88 g/mol |
| Mol. For. | C₄₃H₅₃NO₁₄ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Docetaxel |
| Purity | 95% |
| Therapeutic | Anti-Cancer / Oncology |
| Smileys | CC(O[C@@]1([C@](C[C@@H]2O)([H])OC1)[C@@]([C@@]2(C3=O)C)([H])[C@@H]([C@@](C4(C)C)(C[C@H](OC([C@@H](O)[C@H](C5=CC=CC=C5)NC(OC(C)(C)C)=O)=O)C(C)=C4[C@H]3O)O)OC(C6=CC=CC=C6)=O)=O |
| Canonical Smiles | CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O |
| InchIKey | ZDZOTLJHXYCWBA-KWUUUEAUSA-N |
| Inchl | InChI=1S/C43H53NO14/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)25-17-13-10-14-18-25)33-41(8,34(49)31(47)29(22)40(43,6)7)27(46)19-28-42(33,21-54-28)57-23(2)45/h9-18,26-28,30-33,35,46-48,53H,19-21H2,1-8H3,(H,44,52)/t26-,27-,28+,30-,31+,32-,33-,35-,41+,42-,43+/m0/s1 |
| IUPAC | [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1,9,12-trihydroxy-15-[(2S,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
2-Epi Docetaxel, also known as docetaxel-2'-epimer or RP-56976, is a semi-synthetic analogue of the natural taxoid paclitaxel. It is a potent anticancer agent that is used for the treatment of a variety of solid tumors including breast cancer, non-small cell lung cancer, prostate cancer, gastric cancer, and head and neck cancer.
2-Epi Docetaxel works by inhibiting microtubule depolymerization and causing cell cycle arrest, ultimately leading to tumor cell death. It is administered intravenously and is typically given in combination with other chemotherapy drugs.
In terms of chemical information, 2-Epi Docetaxel has a molecular formula of C43H53NO14 and a molecular weight of 807.88 g/mol. It is a white to off-white powder that is insoluble in water and soluble in ethanol and methanol.
Like most chemotherapy drugs, 2-Epi Docetaxel can cause a range of side effects including hair loss, nausea, vomiting, fatigue, and low blood cell counts. It can also cause more serious side effects such as allergic reactions and peripheral neuropathy. Patients receiving 2-Epi Docetaxel should be closely monitored for any adverse reactions and should follow their healthcare provider's instructions for managing side effects.
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Related Compounds
Docetaxel Impurity B | Docetaxel Impurity 2 | Docetaxel Impurity C | N-Des-t-boc-10-deacetyl-7,10-O-bis{[(2,2,2-trichloroethyl)oxy]carbonyl} Docetaxel | Docetaxel side chain impurity | Docetaxel Impurity 7 (Oxazolidine 4R | Docetaxel Impurity A | Docetaxel Impurity 7 (Na) | Docetaxel 13-Oxo impurity | Docetaxel Related Compound 1 ((2R, 3S)-3-Phenylisoserine Hydrochloride) | N- Formyl Docetaxel | Docetaxel Impurity 4 (Oxazolidine 4S | Desbenzoyl Docetaxel | N-DesBoc Docetaxel | Docetaxel Hydrate | Docetaxel Impurity 20 | Docetaxel Related Compound 2 ((2R, 3S)-Boc-3-Phenylisoserine) | Docetaxel Crotonaldehyde Analog | tert-butyl(4S,5R)-4-formyl-2,2-dimethyl-5-phenyl oxazolidine-3-carboxylate |