Didefluoro Nebivolol

Product Name Didefluoro Nebivolol
Alternate Names Nebivolol Impurities, Impurities of Nebivolol
CAT No. CS-O-31098
CAS No. 129101-33-3
Category Impurities
Stock IN-Stock
Mol. Wt. 369.45 g/mol
Mol. For. C22H27NO4
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Nebivolol
Purity >98%
Smileys O[C@H]([C@]1([H])OC2=CC=CC=C2CC1)CNC[C@@H]([C@@]3([H])OC4=CC=CC=C4CC3)O
Canonical Smiles C1CC2=CC=CC=C2OC1C(CNCC(C3CCC4=CC=CC=C4O3)O)O
InchIKey QSCYKSXNGYFRFZ-UHFFFAOYSA-N
Inchl InChI=1S/C22H27NO4/c24-17(21-11-9-15-5-1-3-7-19(15)26-21)13-23-14-18(25)22-12-10-16-6-2-4-8-20(16)27-22/h1-8,17-18,21-25H,9-14H2
IUPAC 1-(3,4-dihydro-2H-chromen-2-yl)-2-[[2-(3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]ethanol
Controlled No
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Didefluoro Nebivolol is a beta-blocker drug used to treat high blood pressure, also known as hypertension. It works by blocking the action of certain chemicals in the body, such as adrenaline and noradrenaline, which can increase heart rate and blood pressure. By reducing the heart's workload and relaxing blood vessels, Didefluoro Nebivolol helps to lower blood pressure and improve blood flow throughout the body. Chemically, Didefluoro Nebivolol is a selective beta-1 receptor blocker, meaning it specifically targets the beta-1 receptors found in the heart. It is a chiral molecule, meaning that it exists in two mirror-image forms, or enantiomers. The active form of Didefluoro Nebivolol is the S-enantiomer, which is responsible for its blood pressure-lowering effects. Didefluoro Nebivolol is typically administered orally in tablet form, with a recommended starting dose of 5 mg per day. It can be taken with or without food, and doses may be adjusted based on individual response and tolerability. It is important to follow the dosage instructions provided by a healthcare professional and not to abruptly stop taking Didefluoro Nebivolol, as this can cause a rebound increase in blood pressure. Overall, Didefluoro Nebivolol is an effective and well-tolerated treatment option for hypertension, with minimal side effects and a low risk of interactions with other medications. Its selective beta-1 blocking activity and chiral nature make it a unique and valuable addition to the beta-blocker class of drugs.

Related Compounds

Nebivolol Stereoisomer Mixture | Nebivolol Impurity 12 (RR,RR) | Nebivolol Impurity 10 (RS,SR) | Nebivolol Impurity B (SR,SS) | N-Nitroso Nebivolol (Mixture of Diastereomers) | Nebivolol Impurity 11 (SR,SR) | Nebivolol impurity 1 | Nebivolol RSSS Isomer | rel-Desfluoro Nebivolol Impurity | Nebivolol Impurity 3 | Nebivolol Isomer (SRSR+RSRS) | Nebivolol isomers - RSRR | N-Benzyl (-)-Nebivolol | Nebivolol Impurity (RSRR+SRSS) | Nebivolol Impurity 20 (SS,SS) | Nebivolol Impurity 3 (RRSS) (HCl) | Nebivolol Hydrochloride At RRT 1.13 | N-Nitroso Nebivolol | Nebivolol Impurity 8 (SR) | Nebivolol isomers (RSRS+RSSR+SRRS) | Nebivolol Impurity (RRSR+RSRR) | Nebivolol Impurity 4 | Nebivolol lactose adduct | Defluoro Nebivolol (Mixture of Diastereomers) | Nebivolol HCL unwanted isomer Impurity | Nebivolol Impurity 12 | Nebivolol Impurity 6 (SS) | Nebivolol Impurity 1 (RR,SS) | Nebivolol Impurity 34 (RSRR+RRRR) | Nebivolol Impurity 5 | Nebivolol Impurity 7 (RR) | rel-N-Benzyl Nebivolol | Nebivolol RRRS isomer | Nebivolol Hydrochloride At RRT 0.88 | Nebivolol Impurity (SSRS+SRSS) | Nebivolol EP Impurity D | Nebivolol Impurity 2 HCl (SR,RS) | Nebivolol Impurity 17 (RS,SR) | Defluoro Nebivolol | Nebivolol Impurity 14 | Nebivolol Related compound A (RSSR+SRRS) | Nebivolol Impurity 26 | Nebivolol Impurity 9 (RS) | Nebivolol Impurity A | Nebivolol Impurity 13 (SS,SS) |

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