Apixaban Acid Impurity
| Product Name | Apixaban Acid Impurity |
|---|---|
| CAT No. | CS-O-31952 |
| CAS No. | 503614-92-4 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 460.48 g/mol |
| Mol. For. | C₂₅H₂₄N₄O₅ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Therapeutic | Anti-Thrombotics |
| Smileys | COC1=CC=C(C=C1)N2C3=C(CCN(C3=O)C4=CC=C(C=C4)N5CCCCC5=O)C(=N2)C(=O)O |
| Canonical Smiles | COC1=CC=C(C=C1)N2C3=C(CCN(C3=O)C4=CC=C(C=C4)N5CCCCC5=O)C(=N2)C(=O)O |
| InchIKey | PPUHOTDYJQGTAE-UHFFFAOYSA-N |
| Inchl | InChI=1S/C25H24N4O5/c1-34-19-11-9-18(10-12-19)29-23-20(22(26-29)25(32)33)13-15-28(24(23)31)17-7-5-16(6-8-17)27-14-3-2-4-21(27)30/h5-12H,2-4,13-15H2,1H3,(H,32,33) |
| IUPAC | 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Apixaban is a popular anticoagulant medication that is commonly used to treat and prevent blood clots. It works by inhibiting the activity of a protein called factor Xa, which is responsible for blood clotting. However, during the synthesis of apixaban drug substance, an impurity known as Apixaban Acid Impurity may be formed.
Apixaban Acid Impurity (AAI) is a by-product that is generated during the manufacturing process of apixaban. It is a chemical compound that is structurally related to apixaban but lacks its therapeutic activity. AAI is an organic acid that contains two carboxylic acid groups, one of which is derived from the parent apixaban molecule.
The presence of AAI in apixaban drug substance can affect the quality and safety of the medication. Therefore, it is important to monitor and control its levels during the manufacturing process. The maximum allowable limit for AAI in apixaban drug substance is 0.5% as per regulatory guidelines.
In summary, Apixaban Acid Impurity is an undesired by-product that may be formed during the synthesis of apixaban. Its presence in the drug substance can affect the quality and safety of the medication, and therefore, its levels need to be carefully monitored and controlled.
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