2-Amino-6-(benzyloxy)purine, 2-Amino-6-(phenylmethoxy)-9H-purine

2-Amino-6-(benzyloxy)purine and 2-Amino-6-(phenylmethoxy)-9H-purine are two analogs of the purine base, which is an essential component of nucleic acids. These compounds are commonly used in the research field as selective inhibitors of adenosine receptors. They are known to exhibit high affinity towards adenosine receptors and have been used in various studies to understand the role of these receptors in the body. Chemically, both compounds contain an amino group and a purine ring, which are important for their pharmacological activity. The benzyloxy and phenylmethoxy groups attached to the purine ring are responsible for the selectivity towards adenosine receptors. These compounds have also been studied for their potential use as anticancer agents due to their ability to induce apoptosis in cancer cells. In terms of usage, 2-Amino-6-(benzyloxy)purine and 2-Amino-6-(phenylmethoxy)-9H-purine are primarily used in in vitro studies to investigate the role of adenosine receptors in various biological processes such as inflammation, cardiovascular diseases, and neurological disorders. These compounds are also used in drug discovery programs to develop novel adenosine receptor antagonists. Overall, 2-Amino-6-(benzyloxy)purine and 2-Amino-6-(phenylmethoxy)-9H-purine are important compounds in the field of medicinal chemistry and have potential therapeutic applications.