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Levonorgestrel EP Impurity R

Also known as: Levonorgestrel Impurities or impurities of Levonorgestrel
Chemical Name Levonorgestrel EP Impurity R
CAT No. CS-O-32358
CAS Registry# 2322-77-2
Status Prompt Dispatch
Category Impurities
Mol. Wt. 300.44 g/mol
Mol. For. C20H28O2
Hazardous This is not a Hazardous Compound
COA View Sample COA

Additional Information

Controlled No
Parent API Levonorgestrel
Purity 87.84
Smileys CC[C@@]1(C2=O)[C@](CC2)([H])[C@@](CCC3=C4CC=C(OC)C3)([H])[C@]4([H])CC1
Canonical Smiles CCC12CCC3C(C1CCC2=O)CCC4=C3CC=C(C4)OC
Inchl InChI=1S/C20H28O2/c1-3-20-11-10-16-15-7-5-14(22-2)12-13(15)4-6-17(16)18(20)8-9-19(20)21/h5,16-18H,3-4,6-12H2,1-2H3/t16-,17-,18+,20+/m1/s1
IUPAC (8R,9S,13S,14S)-13-ethyl-3-methoxy-4,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-one
Hazardous No

Usage and description

Levonorgestrel is a synthetic progestin hormone used in various hormonal contraceptives. Levonorgestrel EP Impurity R is a known impurity that can be present in certain batches of levonorgestrel due to the synthesis process. This impurity has been identified as (17α)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one. Although Levonorgestrel EP Impurity R is not an active ingredient in hormonal contraceptives, its presence can affect the quality and safety of the final product. Therefore, it is important to monitor its levels during the manufacturing process and ensure that it is within acceptable limits. From a chemical perspective, Levonorgestrel EP Impurity R is a steroid compound with a molecular weight of 308.45 g/mol. Its structure contains a ketone functional group, a double bond, and a hydroxyl group, which are all common features in steroid molecules. The impurity can be detected and quantified using various analytical techniques such as high-performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC-MS). In summary, Levonorgestrel EP Impurity R is a steroid impurity that can be present in levonorgestrel-based hormonal contraceptives. Its monitoring and control are essential to ensure the quality and safety of the final product.

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