2-Nor Latanoprost

2-Nor Latanoprost is a prostaglandin analog used to treat glaucoma and ocular hypertension. It works by reducing the intraocular pressure in the eye, which is the main cause of these conditions. The drug is administered as an eye drop, and the recommended dosage is one drop in the affected eye(s) once daily in the evening. Chemically, 2-Nor Latanoprost is a derivative of latanoprost, which is a naturally occurring prostaglandin F2alpha analog. It differs from latanoprost in that it lacks the 13,14-double bond in the side chain. This modification makes 2-Nor Latanoprost more stable than latanoprost and reduces the risk of degradation. The mechanism of action of 2-Nor Latanoprost involves binding to the prostaglandin F2alpha receptor in the eye, which activates a signaling pathway that increases the outflow of aqueous humor from the eye. This reduces the intraocular pressure and prevents damage to the optic nerve. The drug has been shown to be effective in reducing intraocular pressure in patients with open-angle glaucoma and ocular hypertension. It has also been found to be well-tolerated, with few side effects. The most common side effects include eye irritation, redness, and itching. In conclusion, 2-Nor Latanoprost is a prostaglandin analog used to treat glaucoma and ocular hypertension by reducing intraocular pressure. Its chemical structure is a derivative of latanoprost, and it works by binding to the prostaglandin F2alpha receptor in the eye. The drug is effective and well-tolerated, with few side effects.