Vonoprazan fumarate 13C D3

Product Name Vonoprazan fumarate 13C D3
CAT No. CS-O-32964
CAS No. 881681-01-2 (Unlabeled)
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 465.47 g/mol
Mol. For. C₂₀¹³CH₁₇D₃FN₃O₆S
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Smileys FC1=C(C2=CC(CN[13C]([2H])([2H])[2H])=CN2S(C3=CC=CN=C3)(=O)=O)C=CC=C1.O=C(O)/C=C/C(O)=O
Canonical Smiles CNCC1=CN(C(=C1)C2=CC=CC=C2F)S(=O)(=O)C3=CN=CC=C3.C(=CC(=O)O)C(=O)O
InchIKey ROGSHYHKHPCCJW-WLHGVMLRSA-N
Inchl InChI=1S/C17H16FN3O2S.C4H4O4/c1-19-10-13-9-17(15-6-2-3-7-16(15)18)21(12-13)24(22,23)14-5-4-8-20-11-14;5-3(6)1-2-4(7)8/h2-9,11-12,19H,10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
IUPAC (E)-but-2-enedioic acid;1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine
Controlled No
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Vonoprazan fumarate 13C D3 is a drug that is used in the treatment of gastroesophageal reflux disease (GERD) and other acid-related disorders of the stomach and esophagus. It belongs to a class of drugs known as proton pump inhibitors (PPIs), which work by reducing the amount of acid produced by the stomach. Chemically, Vonoprazan fumarate 13C D3 is a fumarate salt of the deuterated form of Vonoprazan, which is a pyridine-based PPI. The deuterated form of Vonoprazan contains three atoms of deuterium, which replace three hydrogen atoms in the molecule. This modification helps in the identification and quantification of the drug in biological samples using mass spectrometry. Vonoprazan fumarate 13C D3 is available in the form of tablets for oral administration. The recommended dose for adults is 20 mg once daily, to be taken before a meal. The drug has a half-life of about six hours and is metabolized in the liver. It is excreted in the urine and feces. Like other PPIs, Vonoprazan fumarate 13C D3 may cause side effects such as headache, nausea, diarrhea, abdominal pain, and constipation. It may also increase the risk of certain infections, such as pneumonia and Clostridium difficile-associated diarrhea. Therefore, it should be used with caution in patients with a history of these infections. It is also important to consult a healthcare professional before taking this drug, especially if you have liver or kidney disease, or are taking other medications.

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