Crisaborole Impurity 1

Crisaborole Impurity 1 is a chemical compound that is commonly used in the pharmaceutical industry as an impurity in the production of crisaborole. Crisaborole is a topical medication that is used to treat eczema in both adults and children. Crisaborole Impurity 1 is a byproduct of the manufacturing process of crisaborole and is typically present in low concentrations in the final product. Chemically, Crisaborole Impurity 1 is known as 4-cyano-3-(trifluoromethyl)phenol. It has a molecular formula of C8H4F3NO and a molecular weight of 203.12 g/mol. The compound is a white or off-white powder that is soluble in organic solvents like methanol and ethyl acetate. While Crisaborole Impurity 1 is not the active ingredient in crisaborole, it is important to monitor its concentration in the final product. This is because impurities like Crisaborole Impurity 1 can affect the safety and efficacy of a medication. In fact, regulatory agencies like the United States Food and Drug Administration (FDA) have strict guidelines for the acceptable levels of impurities in pharmaceutical products. In conclusion, Crisaborole Impurity 1 is an important chemical compound in the production of crisaborole. While it is not the active ingredient in the medication, it is necessary to monitor its concentration to ensure the safety and efficacy of the final product.