Apremilast D8

Chemical Name Apremilast D8
Alternate Names Apremilast Stable Isotopes, Stable Isotopes of Apremilast
CAT No. CS-O-33021
CAS Registry# 1258597-45-3
Category Stable Isotopes
Stock Enquire
Mol. Wt. 468.55 g/mol
Mol. For. C22H16D8N2O7S
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Apremilast
Smileys C[S](C[C@H](C1=CC(OC([2H])([2H])C([2H])([2H])[2H])=C(OC([2H])([2H])[2H])C=C1)N(C(C2=CC=C3)=O)C(C2=C3NC(C)=O)=O)(=O)=O
Controlled No
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Apremilast D8 is a deuterated version of Apremilast, which is a drug used to treat inflammatory skin conditions such as psoriasis and psoriatic arthritis. The chemical formula of Apremilast D8 is C22H14D8N2O4, indicating that it has several deuterium atoms in its molecular structure. The primary mode of action of Apremilast D8 is as a phosphodiesterase 4 (PDE4) inhibitor. PDE4 is an enzyme that plays a key role in the regulation of inflammatory responses in the body. By inhibiting PDE4, Apremilast D8 helps to reduce inflammation and improve symptoms such as itching, redness, and scaling in patients with psoriasis. Apremilast D8 is typically administered orally, with dosages ranging from 30 to 60 mg per day depending on the severity of the patient's condition. The drug is generally well tolerated, with common side effects including diarrhea, nausea, and headache. In terms of chemical properties, Apremilast D8 is a white to off-white crystalline powder that is slightly soluble in water and ethanol. It has a molecular weight of 370.45 g/mol and a melting point of 228-230°C. Overall, Apremilast D8 is an important drug for the treatment of inflammatory skin conditions, and its unique deuterated structure may offer some advantages over the non-deuterated version in terms of efficacy and safety.

Related Compounds

Apremilast D3 | Apremilast D5 |

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