10α-Methoxy-1-methyl-9,10-dihydrolysergol-D3

10α-Methoxy-1-methyl-9,10-dihydrolysergol-D3, also known as 10-ALD-3 or (−)-10α-Methoxy-1-methyl-9,10-dihydrolysergol, is a chemical compound that is commonly used in research studies related to the serotonin system. It is a stereoisomer of lysergic acid, which is a naturally occurring psychedelic substance found in various species of mushrooms. The primary usage of 10-ALD-3 is in the investigation of the interaction between serotonin receptors and various drugs. It has been found to bind with high affinity to several serotonin receptors, including 5-HT1A, 5-HT2A, and 5-HT2C receptors. Additionally, it has been used as a reference standard in the development and validation of analytical methods used to quantify the concentration of lysergic acid derivatives in biological samples. Chemically, 10-ALD-3 is a semi-synthetic ergot alkaloid. It is derived from lysergic acid, which is found in the ergot fungus. The compound has a molecular formula of C20H25N3O2 and a molar mass of 339.4 g/mol. It is a white crystalline powder that is soluble in methanol, ethanol, and dimethyl sulfoxide. In conclusion, 10α-Methoxy-1-methyl-9,10-dihydrolysergol-D3 is a valuable compound in research studies related to the serotonin system. Its ability to bind with high affinity to several serotonin receptors makes it an important tool in investigating the pharmacology of various drugs. Additionally, its use as a reference standard in the development and validation of analytical methods ensures accurate and reliable measurement of lysergic acid derivatives in biological samples.