Lisinopril EP Impurity I Acetate salt

Product Name Lisinopril EP Impurity I Acetate salt
Alternate Names Lisinopril Impurities, Impurities of Lisinopril
CAT No. CS-O-33337
CAS No. 927819-64-5
Category Impurities
Stock IN-Stock
Mol. Wt. 567.7 g/mol
Mol. For. C31H41N3O7
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Lisinopril
Therapeutic Anti-Hypertensives
Smileys O=C([C@H]1N(C([C@@H](N[C@H](C(O)=O)CCC2=CC=CC=C2)CCCCN[C@H](C(O)=O)CCC3=CC=CC=C3)=O)CCC1)O
Canonical Smiles C1CC(N(C1)C(=O)C(CCCCNC(CCC2=CC=CC=C2)C(=O)O)NC(CCC3=CC=CC=C3)C(=O)O)C(=O)O
InchIKey MKOWVLMGJKGFMF-MBKURTIGSA-N
Inchl InChI=1S/C31H41N3O7/c35-28(34-21-9-15-27(34)31(40)41)24(33-26(30(38)39)19-17-23-12-5-2-6-13-23)14-7-8-20-32-25(29(36)37)18-16-22-10-3-1-4-11-22/h1-6,10-13,24-27,32-33H,7-9,14-21H2,(H,36,37)(H,38,39)(H,40,41)/t24-,25?,26-,27-/m0/s1
IUPAC (2S)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]-6-[(1-carboxy-3-phenylpropyl)amino]hexanoyl]pyrrolidine-2-carboxylic acid
Controlled No
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Lisinopril EP Impurity I, also known as (2S)-1-[(2S,5S)-2,5-dimethyl-4-oxo-1,3-thiazolidin-3-yl]propan-2-one, is a chemical compound that is commonly used in the pharmaceutical industry as a reference standard for the analysis of Lisinopril, a medication used to treat high blood pressure and heart failure. Lisinopril EP Impurity I is a colorless to pale yellow solid that is soluble in organic solvents like methanol and ethanol. Chemically, Lisinopril EP Impurity I is a thiazolidinone derivative, which is a cyclic amide containing a sulfur atom and a nitrogen atom in the ring. This compound is synthesized through a multi-step process that involves the reaction of 2,5-dimethyl-1,3-thiazolane-4-carboxylic acid with acetic anhydride, followed by the addition of sodium borohydride and acetic acid. Lisinopril EP Impurity I is important in the pharmaceutical industry because it is used as a reference standard to ensure the quality and purity of Lisinopril. It is also used in the development and validation of analytical methods for the quantification of Lisinopril in drug formulations. The use of this impurity and its reference standard is crucial in the production of safe and effective medications for patients.

Related Compounds

N-trifluoroacetyl Lisinopril Intermediate | Lisinopril-D4 | Lisinopril EP Impurity G | Lisinopril-D8 | Lisinopril EP Impurity F | N-Benzyloxycarbonyl (S)-Lisinopril | Lisinopril EP Impurity D | Lisinopril Des-Proline dimer - II | Lisinopril EP impurity C Acetate salt | N2-(1-Ethoxycarbonyl-3-oxo-3-phenylpropyl)-N6-trifluoroacetyl-L-lysine | N-Benzyloxycarbonyl Lisinopril Cyclohexyl Analogue Ethyl Methyl Diester | N-Benzyloxycarbonyl (S)-Lisinopril Ethyl Methyl Diester | Lisinopril EP Impurity J | N-(1-Carboxy-3-phenylpropyl)-S-lisinopril (Mixture of diastereomers) | Lisinopril EP Impurity E | Lisinopril EP Impurity A | Lisinopril Intermediate | Lisinopril SRS-Diastereomer | Lisinopril EP Impurity A |

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