Des-benzyl Benidipine

Des-benzyl benidipine is a chemical compound that belongs to the class of dihydropyridine calcium channel blockers. It is a derivative of benidipine and is commonly used in the treatment of hypertension, angina pectoris, and other cardiovascular diseases. Des-benzyl benidipine works by blocking the entry of calcium ions into the smooth muscle cells of the blood vessels, resulting in dilation and relaxation of the vessels, thereby reducing blood pressure and improving blood flow. Chemically, des-benzyl benidipine is a white to off-white crystalline powder with a molecular formula of C26H30N2O5 and a molecular weight of 458.54 g/mol. It has a melting point of 141-142°C and is soluble in organic solvents like ethanol, methanol, and chloroform. The compound is stable under normal conditions and can be stored in a cool and dry place away from light. In terms of usage, des-benzyl benidipine is usually administered orally in the form of tablets or capsules. The recommended dosage may vary depending on the severity of the condition, age, and overall health of the patient. It is important to follow the dosage instructions provided by the healthcare provider and to not exceed the prescribed dose. Overall, des-benzyl benidipine is an effective calcium channel blocker that is widely used in the treatment of hypertension and other cardiovascular diseases. Its chemical properties and mechanism of action make it a valuable tool in managing these conditions and improving patient outcomes.