Loteprednol etabonate 17-Carboxylic acid Methyl ester

Loteprednol etabonate 17-Carboxylic acid Methyl ester is a synthetic corticosteroid that is commonly used in the treatment of various types of eye inflammation. It is a derivative of loteprednol, which is a corticosteroid that has been modified to reduce its potential for adverse effects such as elevated intraocular pressure (IOP). This medication works by inhibiting the production of inflammatory mediators such as prostaglandins, leukotrienes and histamines, thereby reducing inflammation and swelling in the eye. It is commonly used to treat a variety of ocular conditions including allergic conjunctivitis, iritis, keratitis, uveitis, and other types of ocular inflammation. Loteprednol etabonate 17-Carboxylic acid Methyl ester is administered as an eye drop solution, with the recommended dosage and frequency varying depending on the condition being treated and the severity of the inflammation. As with all medications, this drug may cause side effects such as blurred vision, eye irritation, itching, redness, or tearing. In terms of chemical information, Loteprednol etabonate 17-Carboxylic acid Methyl ester has a molecular formula of C26H32ClNO7, and a molecular weight of 521.99 g/mol. It is a white crystalline powder that is practically insoluble in water, but soluble in organic solvents such as ethanol and methanol. Its chemical structure features a carboxylic acid ester group, which is responsible for its anti-inflammatory properties.