Bempedoic acid-D5

Bempedoic acid-D5 is a deuterated form of bempedoic acid, a medication used to lower cholesterol levels in the blood. Bempedoic acid-D5 is a recently developed isotopically labeled version of bempedoic acid, which is used for research and development purposes. The primary use of bempedoic acid-D5 is in the development of novel therapies for the treatment of cardiovascular diseases, specifically those related to high cholesterol levels. Bempedoic acid-D5 is used in pharmacokinetic studies to better understand the metabolism, distribution, and elimination of bempedoic acid in the body. The deuterium label provides a unique tool to study the pharmacokinetics of bempedoic acid and its metabolites with high precision and accuracy. Chemically, bempedoic acid-D5 is a prodrug that is converted to the active form, bempedoic acid, in the liver. Bempedoic acid acts by inhibiting an enzyme called ATP citrate lyase, which is responsible for producing cholesterol in the liver. As a result, bempedoic acid decreases the production of cholesterol in the liver, leading to lower cholesterol levels in the blood. In conclusion, bempedoic acid-D5 is a valuable tool for researchers in the development of novel therapies for the treatment of cardiovascular diseases. Its unique isotopic label allows for precision and accuracy in pharmacokinetic studies, leading to a better understanding of the metabolism and elimination of bempedoic acid in the body.