3-Hydroxy Midostaurin D5
| Product Name | 3-Hydroxy Midostaurin D5 |
|---|---|
| Alternate Names | Midostaurin Stable Isotopes, Stable Isotopes of Midostaurin |
| CAT No. | CS-O-35573 |
| CAS No. | 179237-49-1 (Unlabeled) |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | 605.69 g/mol |
| Mol. For. | C36H27D5N4O5 |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Midostaurin |
| Smileys | O=C(N([C@H]1C[C@@](O2)([H])N3C4=CC=CC=C4C5=C3C6=C(C7=CC=CC=C7N6[C@@]2(C)C[C@@H]1OC)C(C(O)N8)=C5C8=O)C)C9=C([2H])C([2H])=C([2H])C([2H])=C9[2H] |
| Canonical Smiles | CC1=CC2=C(C=C1)N=C(N2)C |
| InchIKey | MVHOAOSHABGEFL-UHFFFAOYSA-N |
| Inchl | InChI=1S/C9H10N2/c1-6-3-4-8-9(5-6)11-7(2)10-8/h3-5H,1-2H3,(H,10,11) |
| IUPAC | 2,6-dimethyl-1H-benzimidazole |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
3-Hydroxy Midostaurin D5 is a chemical compound used in medical research and drug development. It is a deuterated derivative of the drug midostaurin, which is used to treat certain types of cancer. The deuterium labeling of 3-Hydroxy Midostaurin D5 provides a stable isotope for use in pharmacokinetic and metabolic studies.
The chemical structure of 3-Hydroxy Midostaurin D5 includes a pyrido[2,3-d]pyrimidine core with a hydroxyl (OH) group and a deuterium atom (D) attached to it. The hydroxyl group is important for the compound's biological activity, as it can form hydrogen bonds with target proteins.
Studies have shown that 3-Hydroxy Midostaurin D5 is metabolized in the liver by cytochrome P450 enzymes, which convert it into several metabolites. These metabolites are excreted in the urine and feces. The pharmacokinetics of 3-Hydroxy Midostaurin D5 have been studied in both animal and human models, with results indicating that it has good oral bioavailability and a relatively long half-life.
Overall, 3-Hydroxy Midostaurin D5 is a valuable tool for researchers studying midostaurin and related drugs. Its stable isotope labeling and metabolic properties make it an important compound for understanding the pharmacology of these drugs and developing new treatments for cancer and other diseases.
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Related Compounds
Midostaurin 13C6 | O-Desmethyl Midostaurin D5 | Midostaurin metabolite-13C6 (CGP52421) | O-Desmethyl Midostaurin-13C6 | Midostaurin D5 |