(3S,5S)-Atorvastatin Calcium Salt Trihydrate

(3S,5S)-Atorvastatin Calcium Salt Trihydrate, commonly known as Atorvastatin, is a white crystalline powder that is used to treat high cholesterol and reduce the risk of heart diseases. It is a potent inhibitor of the enzyme HMG-CoA reductase, which is responsible for the production of cholesterol in the liver. Atorvastatin acts by blocking the production of cholesterol and increasing the level of high-density lipoprotein (HDL) or “good” cholesterol in the blood. Atorvastatin is available in tablet form and is usually taken once daily, with or without food. The dosage and duration of treatment depend on the patient’s medical condition and response to the medication. Atorvastatin is well-tolerated by most patients, but some may experience side effects such as muscle pain, stomach upset, and headache. In terms of chemical information, Atorvastatin has a molecular weight of 1209.42 g/mol and a molecular formula of C66H68CaF2N4O10. The calcium salt trihydrate form of Atorvastatin is commonly used in pharmaceutical formulations due to its stability and solubility properties. The drug has a high degree of lipophilicity and is extensively metabolized in the liver. The elimination half-life of Atorvastatin is approximately 14 hours, and it is primarily excreted in the feces. In conclusion, (3S,5S)-Atorvastatin Calcium Salt Trihydrate is a widely used medication for the treatment of high cholesterol and reducing the risk of heart diseases. It is a potent inhibitor of HMG-CoA reductase and acts by reducing the production of cholesterol in the liver. Atorvastatin is well-tolerated by most patients and is available in tablet form. Its chemical properties make it a suitable candidate for pharmaceutical formulations.