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Product Information

Product (p-Fluoro-DL-(phenyl-d4)alanine)
CAT No. CS-O-36594
CAS No. 101144-78-9
Status price
Category Stable Isotopes
Mol. Wt. 374.41 mol/g
Mol. For. C18H12D8F2N2O4
Hazardous This is not a Hazardous Compound

Product Description

P-Fluoro-DL-(phenyl-d4)alanine, also known as FDPPA, is a synthetic amino acid derivative that is widely used in pharmaceutical research. It is a non-natural amino acid analog of phenylalanine, which has been deuterated at the phenyl ring and has a fluorine atom attached to the para position of the phenyl ring. This chemical compound is used as a molecular probe in positron emission tomography (PET) imaging studies of the brain, especially in research related to the dopamine and serotonin neurotransmitter systems. FDPPA is able to selectively bind to the dopamine and serotonin transporters, which are proteins responsible for reuptake of these neurotransmitters from the synaptic cleft back into the presynaptic neuron. By labeling FDPPA with a radioisotope, such as carbon-11 or fluorine-18, researchers can study the distribution and density of dopamine and serotonin transporters in the brain, which can provide insight into neurological disorders such as Parkinson's disease and depression. FDPPA has a molecular formula of C9H7D4FNO2 and a molecular weight of 197.21 g/mol. The deuterium substitution at the phenyl ring of the amino acid allows for easy differentiation from endogenous phenylalanine in biological systems. The fluorine atom at the para position of the phenyl ring enhances the binding affinity of the compound to the dopamine and serotonin transporters.

Additional Information

Packing Product will be supplied in Vials, in certain conditions we also use 'Septa Vials'
Controlled No
Smileys NC(C(O)=O)CC1=C([2H])C([2H])=C(F)C([2H])=C1[2H].C[C@@H](C(O)=O)NC2=C([2H])C([2H])=C(F)C([2H])=C2[2H]
Hazardous No

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Safety & Handling Information

General Information Use proper personal protective equipment
Handling Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Engineering Control Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels.
Clothing Wear appropriate protective clothing to minimize contact with skin.
Skin Wear appropriate protective gloves and clothing to prevent skin exposure.
Eyes Wear safety glasses and chemical goggles if splashing is possible.
Inhalation Remove from exposure and move to fresh air immediately.

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Sample Label

logo (p-Fluoro-DL-(phenyl... www.clearsynth.com 
 CAT : CS-O-36594 BATCH : CSC-WWW0757

 MF: C18H12D8F2N2O4
 CAS: 101144-78-9
 Date of Anaysis: 28-Aug-2023
 Retest Date: 28-Jun-2026
MW: 374.41

Store at refrigerator (2-8C)
Qty: 60 MG 
 Only for R & D and Analytical purpose, Not for Human Consumption.

Sample Packaging

Sample Packaging

Sample Vials

Sample Vials