Ivermectin 8a-oxo-H2B1a

Ivermectin 8a-oxo-H2B1a is a semi-synthetic derivative of Ivermectin, which is an antiparasitic medication used to treat a range of parasitic infections in humans and animals. It is a macrocyclic lactone compound that works by binding to the glutamate-gated chloride channels in nerve and muscle cells of the parasites, leading to paralysis and death of the parasites. Ivermectin 8a-oxo-H2B1a is used primarily in veterinary medicine to treat parasitic infections in livestock such as cattle, sheep, and horses. It is also used in dogs and cats to treat ear mites and other parasitic infections. In humans, Ivermectin 8a-oxo-H2B1a has been studied as a potential treatment for river blindness (onchocerciasis) and other parasitic infections, but its use in humans is limited due to safety concerns and lack of clinical evidence. The chemical structure of Ivermectin 8a-oxo-H2B1a includes two lactone rings and a side chain containing a keto group. It has a molecular weight of 892.1 g/mol and a melting point of 205-207°C. The compound is soluble in organic solvents such as ethanol and acetone, but insoluble in water. In conclusion, Ivermectin 8a-oxo-H2B1a is a semi-synthetic derivative of Ivermectin that is primarily used in veterinary medicine to treat parasitic infections in livestock. Its potential use in humans is limited, but it remains an important tool in the fight against parasitic infections in animals.