(S)-Stiripentol Glucoronide-D9

(S)-Stiripentol glucoronide-D9 is a deuterated derivative of (S)-Stiripentol glucoronide, which is a metabolite of Stiripentol. Stiripentol is an anticonvulsant medication that is used in the treatment of epilepsy, specifically for the treatment of Dravet syndrome. The chemical formula of (S)-Stiripentol glucoronide-D9 is C21H11D9NO11. (S)-Stiripentol glucoronide-D9 is primarily used in clinical research studies to investigate the pharmacokinetics and metabolism of Stiripentol. Pharmacokinetics is the study of how a drug is absorbed, distributed, metabolized, and eliminated from the body. This deuterated derivative of (S)-Stiripentol glucoronide is used as a stable isotope-labeled internal standard in mass spectrometry-based bioanalysis methods for the quantitative analysis of Stiripentol and its metabolites in biological samples. The glucoronidation of Stiripentol, which leads to the formation of (S)-Stiripentol glucoronide, is an important metabolic pathway of the drug. Glucuronidation is a process by which the liver converts drugs and other substances into more water-soluble compounds that can be easily eliminated from the body. The study of the metabolism of Stiripentol and its metabolites, including (S)-Stiripentol glucoronide-D9, is important for the optimization of the drug's efficacy and safety in the treatment of epilepsy.