N-nitroso-N-methyl-4-aminobutyric acid (1,2,3,4-13C4)

N-nitroso-N-methyl-4-aminobutyric acid (1,2,3,4-13C4), also known as NMABA, is a chemical compound that has many uses in the field of biochemistry and biomedical research. This compound is a member of the N-nitroso family of compounds, which are known to be powerful carcinogens. NMABA is used as a stable isotope-labeled internal standard for the analysis of N-nitroso compounds in biological samples. It is used to measure the levels of these compounds in various tissues and fluids, including blood, urine, and breast milk. NMABA is a white crystalline powder that is soluble in water and has a melting point of 178-180 °C. The molecular formula of NMABA is C9H15N3O4, and its molecular weight is 233.24 g/mol. This compound contains four carbon-13 atoms, which makes it useful for stable isotope labeling experiments. In terms of its chemical properties, NMABA is a nitrosamine derivative of the amino acid methionine. It is formed through the nitrosation of methionine and is known to be a potent carcinogen. NMABA has been shown to induce tumors in various animal models, including rats and mice. In summary, N-nitroso-N-methyl-4-aminobutyric acid (1,2,3,4-13C4) is a powerful compound that has many uses in the field of biochemistry and biomedical research. Its stable isotope labeling properties make it useful for the analysis of N-nitroso compounds in biological samples, while its chemical properties make it a potent carcinogen.