N-nitrosopiperazine Palbociclib
Also known as: Palbociclib Nitrosamine Impurities or nitrosamine impurities of Palbociclib| Product Name | N-nitrosopiperazine Palbociclib |
|---|---|
| Alternate Names | Palbociclib Impurities, Impurities of Palbociclib |
| CAT No. | CS-O-37587 |
| CAS No. | Not Available |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 476.53 g/mol |
| Mol. For. | C₂₄H₂₈N₈O₃ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Palbociclib |
| Smileys | O=C1C(C(C)=O)=C(C)C2=CN=C(NC3=NC=C(N4CCN(N=O)CC4)C=C3)N=C2N1C5CCCC5 |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
N-nitrosopiperazine Palbociclib is a chemical compound that is used in the treatment of breast cancer. It is an inhibitor of cyclin-dependent kinases (CDKs) 4 and 6, which are enzymes that regulate the cell cycle. By inhibiting these enzymes, N-nitrosopiperazine Palbociclib can slow down the growth and division of cancer cells, which can help to stop the spread of the cancer.
The chemical formula for N-nitrosopiperazine Palbociclib is C24H29N7O2, and its molecular weight is 447.54 g/mol. It is a white to off-white powder that is slightly soluble in water and has a melting point of 178-182°C. The compound is typically administered orally in the form of tablets.
N-nitrosopiperazine Palbociclib has been extensively studied in clinical trials and has been shown to be effective in the treatment of hormone receptor-positive, HER2-negative breast cancer. It is often used in combination with other cancer drugs, such as letrozole or fulvestrant.
While N-nitrosopiperazine Palbociclib is generally well-tolerated by patients, it can cause some side effects, including fatigue, nausea, and diarrhea. It may also cause a decrease in white blood cell counts, which can increase the risk of infection.
In conclusion, N-nitrosopiperazine Palbociclib is an important drug in the treatment of breast cancer, and its use is supported by a wealth of clinical data. While it does have some potential side effects, it is generally safe and well-tolerated by patients.
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Related Compounds
Palbociclib Lactose adduct 2 | Palbociclib Impurity 61 | Palbociclib Impurity 57 | Palbociclib Impurity 59 | Palbociclib Impurity 5 | Palbociclib Impurity 13 | Palbociclib Fumaric Acid | Palbociclib Impurity 16 | Palbociclib dimer Impurity | Palbociclib Impurity 60 | Palbociclib Impurity 12 | N- Nitroso Palbociclib Impurity | Palbociclib Impurity 19 | Palbociclib Sulfamic Acid | Palbociclib Lactose adduct 1 | Palbociclib Millard reaction Impurity | Palbociclib Impurity 3 | Palbociclib Impurity 7 | Palbociclib Des Acetyl N-Oxide | Palbociclib Citric acid adduct | PD 0332991 hydrochloride - Palbociclib hydrochloride | N-Nitroso butoxy vinyl Palbociclib | Palbociclib Impurity 9 | N-Nitroso 6-Desacetyl-6-bromo-N-Boc Palbociclib | Palbociclib Impurity-G | Palbociclib Impurity 19 | Palbociclib Impurity D | Palbociclib Vinyl impurity | Palbociclib Acetic Acid Adduct | Palbociclib Impurity 22 | Palbociclib Nitroso Impurity 2 | Palbociclib Impurity 1 | N-Boc protected Palbociclib dimer | Palbociclib Impurity 15 | Palbociclib Tartaric acid adduct | Palbociclib Impurity 8 | Palbociclib Impurity 32 | Palbociclib Impurity 31 | Palbociclib Impurity 10 | Palbociclib Impurity 4 | Palbociclib Nitroso Impurity 1 | Palbociclib Impurity 62 | Palbociclib Impurity C | Tert-butyl 4-(2-aminopyridin-3-yl)piperazine-1-carboxylate | Palbociclib Impurity 11 | Palbociclib Impurity 37 | Tert-butyl 4-(4-aminopyridin-3-yl) | Palbociclib oxobutanoic acid Impurity | Palbociclib Impurity | Palbociclib Impurity 6 | Palbociclib Impurity 58 | Palbociclib Impurity 17 HCl salt | Palbociclib Impurity 21 |