N-Nitroso-Nadolol
Also known as: Nadolol Nitrosamine Impurities or nitrosamine impurities of Nadolol| Product Name | N-Nitroso-Nadolol |
|---|---|
| Alternate Names | Nadolol Impurities, Impurities of Nadolol |
| CAT No. | CS-O-38045 |
| CAS No. | 134720-06-2 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 338.40 g/mol |
| Mol. For. | C₁₇H₂₆N₂O₅ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Nadolol |
| Canonical Smiles | CC(C)(C)N(CC(COC1=CC=CC2=C1CC(C(C2)O)O)O)N=O |
| InchIKey | UDVFPQUAVVJONH-UHFFFAOYSA-N |
| Inchl | InChI=1S/C17H26N2O5/c1-17(2,3)19(18-23)9-12(20)10-24-16-6-4-5-11-7-14(21)15(22)8-13(11)16/h4-6,12,14-15,20-22H,7-10H2,1-3H3 |
| IUPAC | N-tert-butyl-N-[3-[(6,7-dihydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)oxy]-2-hydroxypropyl]nitrous amide |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
N-Nitroso-Nadolol is a chemical compound that belongs to the family of nitrosamines. It is commonly used as a pharmaceutical drug for the treatment of hypertension, angina pectoris, and cardiac arrhythmias. Nadolol works by blocking beta-adrenergic receptors in the heart, which reduces the heart rate and blood pressure. The nitrosamine moiety of N-Nitroso-Nadolol is believed to enhance the drug’s activity and effectiveness.
N-Nitroso-Nadolol has been extensively studied for its potential carcinogenicity. Nitrosamines are known to be potent carcinogens, and their presence in drugs and food products has raised concerns about their safety. However, studies have shown that the risk of cancer from the use of N-Nitroso-Nadolol is negligible.
The chemical structure of N-Nitroso-Nadolol consists of a nadolol molecule with a nitroso group attached to one of its nitrogen atoms. The compound has a molecular weight of 308.3 g/mol and a melting point of 158-160°C. It is soluble in water, ethanol, and chloroform.
In conclusion, N-Nitroso-Nadolol is a pharmaceutical drug that is used for the treatment of cardiovascular diseases. While its nitrosamine moiety has raised concerns about its safety, studies have shown that the risk of cancer from its use is minimal. It is important to always consult a healthcare professional before taking any medication.
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Related Compounds
Nadolol EP Impurity B | Nadolol EP Impurity A | Nadolol EP Impurity E | Nadolol Epoxide Impurity | Nadolol EP Impurity D | Nadolol EP Impurity G | Nadolol EP Impurity F | NADOLOL IMPURITY 6 | NADOLOL IMPURITY 8 | NADOLOL IMPURITY 4 HCL | Nadolol EP Impurity C | NADOLOL IMPURITY 7 HCL | cis-5,6,7,8-Tetrahydro-1,6,7-naphthalenetriol | De(2,3-dihydroxy) Nadolol Hydrochloride |