3-(3,5-difluoro-2-methoxyphenyl)-5-(1-(1-(methylsulfonyl)piperidin-4-yl)-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine-D7
| Product Name | 3-(3,5-difluoro-2-methoxyphenyl)-5-(1-(1-(methylsulfonyl)piperidin-4-yl)-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine-D7 |
|---|---|
| CAT No. | CS-O-38244 |
| CAS No. | 1613711-28-6 (Unlabeled) |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | 494.57 g/mol |
| Mol. For. | C23H16D7F2N5O3S |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Smileys | O=S(N1C([2H])([2H])CC(N2N=CC(C3=CN=C(NC=C4C5=CC(F)=CC(F)=C5OC([2H])([2H])[2H])C4=C3)=C2)CC1([2H])[2H])(C)=O |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
3-(3,5-difluoro-2-methoxyphenyl)-5-(1-(1-(methylsulfonyl)piperidin-4-yl)-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine-D7 is a deuterated form of a potent and selective inhibitor of protein kinase B (PKB/AKT). PKB is a crucial signaling molecule involved in the regulation of cell survival, proliferation, and metabolism. The compound is used in research studies that investigate the role of PKB in various cellular processes and diseases, including cancer.
The chemical formula of 3-(3,5-difluoro-2-methoxyphenyl)-5-(1-(1-(methylsulfonyl)piperidin-4-yl)-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine-D7 is C24H18D7F2N5O3S, and its molecular weight is 479.58 g/mol. The compound has a melting point of approximately 240-242 °C.
In vitro studies have shown that 3-(3,5-difluoro-2-methoxyphenyl)-5-(1-(1-(methylsulfonyl)piperidin-4-yl)-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine-D7 inhibits the activity of PKB with high potency and selectivity. The deuterated form of the compound is used in pharmacokinetic studies to determine the metabolic fate and distribution of the drug in vivo.
Overall, 3-(3,5-difluoro-2-methoxyphenyl)-5-(1-(1-(methylsulfonyl)piperidin-4-yl)-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine-D7 is a valuable tool in the study of PKB signaling and its role in disease.
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