N-Nitrososotalol (Mixture of isomers)
Also known as: Sotalol Nitrosamine Impurities or nitrosamine impurities of Sotalol| Product Name | N-Nitrososotalol (Mixture of isomers) |
|---|---|
| Alternate Names | Sotalol Impurities, Impurities of Sotalol |
| CAT No. | CS-O-38247 |
| CAS No. | 134720-07-3 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 301.4 g/mol |
| Mol. For. | C12H19N3O4S |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Sotalol |
| Smileys | CS(=O)(NC1=CC=C(C(O)CN(C(C)C)N=O)C=C1)=O |
| Canonical Smiles | CC(C)N(CC(C1=CC=C(C=C1)NS(=O)(=O)C)O)N=O |
| InchIKey | JRGLEYZCDAJXQF-UHFFFAOYSA-N |
| Inchl | InChI=1S/C12H19N3O4S/c1-9(2)15(14-17)8-12(16)10-4-6-11(7-5-10)13-20(3,18)19/h4-7,9,12-13,16H,8H2,1-3H3 |
| IUPAC | N-[4-[1-hydroxy-2-[nitroso(propan-2-yl)amino]ethyl]phenyl]methanesulfonamide |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
N-Nitrososotalol is a complex mixture of isomers that has been extensively studied for its potential as a carcinogen. This compound is formed by the reaction of sotalol, a beta-blocker medication used to treat arrhythmias, with nitrous acid. The resulting mixture of isomers is a light yellow, oily liquid that is soluble in water and organic solvents.
Due to its potential carcinogenic properties, N-Nitrososotalol has been the subject of numerous studies aimed at understanding its mode of action and potential health effects. It has been shown to induce DNA damage and mutations in cells, as well as to promote the growth of tumors in animal models.
In addition to its potential as a carcinogen, N-Nitrososotalol may also have other biological effects. It has been shown to inhibit the activity of certain enzymes involved in the metabolism of drugs and other compounds, which could lead to altered pharmacokinetics and potential drug interactions.
Overall, the use of N-Nitrososotalol is highly regulated due to its potential health effects. It is typically only used in research settings, and there are strict guidelines in place for handling and disposing of this compound.
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Related Compounds
Oxo Sotalol Hydrochloride | Sotalol EP Impurity B | Sotalol EP Impurity D | Sotalol Related Compound A |