Beta-d-N4-hydroxycytidine

1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(hydroxyimino)-3,4-dihydropyrimidin-2(1H)-one, also known as DHP or dihydropyrimidinone, is a chemical compound with a unique structure and a wide range of applications. DHP is commonly used in the synthesis of novel pharmaceuticals, agrochemicals, and biologically active compounds. It acts as a potent inhibitor of dihydroorotate dehydrogenase, an essential enzyme involved in the biosynthesis of pyrimidine nucleotides. This mechanism of action makes it a promising candidate for the development of antitumor, antiviral, and immunosuppressive drugs. In addition, DHP is used as a building block in the synthesis of various inhibitors of protein kinases and G protein-coupled receptors. It has also been shown to exhibit anti-inflammatory and antioxidant properties, making it a potential therapeutic agent in the treatment of inflammatory diseases such as arthritis and asthma. From a chemical perspective, DHP is a crystalline solid with a molecular formula of C10H14N2O6. It has a molecular weight of 258.23 g/mol and a melting point of 232-234 °C. DHP is soluble in water, ethanol, and methanol, and is stable under standard laboratory conditions. In conclusion, 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(hydroxyimino)-3,4-dihydropyrimidin-2(1H)-one, or DHP, is a versatile and valuable compound with a range of potential applications in the fields of medicinal chemistry, agrochemistry, and biochemistry.