N-nitroso Quinapril

N-nitroso Quinapril is a nitrosamine-containing compound and a derivative of the angiotensin-converting enzyme (ACE) inhibitor Quinapril. It is primarily used in the treatment of hypertension and congestive heart failure. It works by blocking the action of ACE, which reduces the production of angiotensin II, a potent vasoconstrictor that increases blood pressure. N-nitroso Quinapril is used in combination with other medications to provide a more effective treatment for hypertension. Chemically, N-nitroso Quinapril is a yellow crystalline solid with a molecular formula of C25H31N5O4 and a molecular weight of 477.55 g/mol. It is a highly reactive compound that can easily form adducts with other biomolecules in the body, potentially leading to DNA damage and mutagenesis. Additionally, exposure to N-nitroso Quinapril has been linked to an increased risk of developing certain types of cancer. Due to its potential carcinogenic properties, the use of N-nitroso Quinapril is highly regulated in many countries. It is classified as a probable human carcinogen by the International Agency for Research on Cancer (IARC) and is subject to strict limits on its use and maximum residual levels in food products. Patients taking N-nitroso Quinapril should be monitored closely for any signs of adverse effects and should discuss any concerns with their healthcare provider.