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Celecoxib nitroso impurity

Also known as: Celecoxib Nitrosamine Impurities or nitrosamine impurities of Celecoxib Also known as: Celecoxib Impurities or impurities of Celecoxib
Chemical Name Celecoxib nitroso impurity
CAT No. CS-O-41115
Status Under Certification (Usually dispatched in 5 days)
Category Impurities
Mol. Wt. 412.08 g/mol
Mol. For. C17H15F3N4O3S
Hazardous This is not a Hazardous Compound
COA View Sample COA

Additional Information


Controlled No
Parent API Celecoxib
Hazardous No


Usage and description


Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation. However, during its production, it can sometimes contain impurities such as Celecoxib nitroso impurity. This impurity is a potential carcinogen and can pose a risk to human health. Celecoxib nitroso impurity is a byproduct of the manufacturing process of Celecoxib. It is formed when nitrites present in the manufacturing process react with the amine group in Celecoxib. Nitrosamines are known to be highly reactive and can cause DNA damage, leading to cancer. Therefore, the presence of this impurity in Celecoxib can be a cause for concern. To ensure the safety of the drug, manufacturers must adhere to strict regulations set by regulatory authorities. The amount of Celecoxib nitroso impurity in the drug must not exceed the acceptable limits set by regulatory authorities. In addition, the drug must undergo rigorous testing to ensure that it is safe for human consumption. In conclusion, Celecoxib nitroso impurity is a potential health hazard and manufacturers must take necessary measures to ensure that the drug is free from this impurity. Patients must also be aware of the potential risks associated with this impurity and should consult their healthcare provider if they have any concerns.

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