Sildenafil dimer-D8
| Product Name | Sildenafil dimer-D8 |
|---|---|
| Alternate Names | Sildenafil Stable Isotopes, Stable Isotopes of Sildenafil |
| CAT No. | CS-O-41251 |
| CAS No. | 1346602-67-2(unlabeled) |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 842.34 g/mol |
| Mol. For. | C38H38D8N10O8S2 |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Sildenafil |
| Canonical Smiles | CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)S(=O)(=O)C5=CC(=C(C=C5)OCC)C6=NC7=C(C(=O)N6)N(N=C7CCC)C)OCC)C |
| InchIKey | OPIJAYPVGDPKAA-UHFFFAOYSA-N |
| Inchl | InChI=1S/C38H46N10O8S2/c1-7-11-27-31-33(45(5)43-27)37(49)41-35(39-31)25-21-23(13-15-29(25)55-9-3)57(51,52)47-17-19-48(20-18-47)58(53,54)24-14-16-30(56-10-4)26(22-24)36-40-32-28(12-8-2)44-46(6)34(32)38(50)42-36/h13-16,21-22H,7-12,17-20H2,1-6H3,(H,39,41,49)(H,40,42,50) |
| IUPAC | 5-[2-ethoxy-5-[4-[4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-5-yl)phenyl]sulfonylpiperazin-1-yl]sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Sildenafil dimer-D8 is a deuterated form of Sildenafil, a medication used to treat erectile dysfunction and pulmonary arterial hypertension. The dimer-D8 form of Sildenafil is created by replacing some of the hydrogen atoms with deuterium atoms, which makes it useful in research and clinical studies due to its unique chemical properties.
Sildenafil dimer-D8 works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which is responsible for breaking down cyclic guanosine monophosphate (cGMP) in the body. By inhibiting PDE5, Sildenafil dimer-D8 increases the levels of cGMP in the body, which causes smooth muscle relaxation and increased blood flow to the penis, resulting in an erection.
The chemical formula for Sildenafil dimer-D8 is C22H25D8N7O3S and its molecular weight is 523.65 g/mol. It is a white to off-white crystalline powder that is soluble in water, ethanol, and dimethyl sulfoxide.
In clinical studies, Sildenafil dimer-D8 has been used as a tracer to study the pharmacokinetics and metabolism of Sildenafil in the body. It has also been used to study drug-drug interactions and to assess the bioavailability of Sildenafil in different formulations.
Overall, Sildenafil dimer-D8 is a valuable tool in the field of pharmaceutical research and has the potential to provide important insights into the mechanisms of action and pharmacokinetics of Sildenafil and other PDE5 inhibitors.
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Related Compounds
Methisosildenafil-d4 | Pyrazole N-Demethyl Sildenafil-d3 | Desethyl Sildenafil D3 | Propoxyphenyl thiohydroxyhomosildenafil-d4 | Sildenafil D8 | Thiosildenafil-d3 | Homo sildenafil-d5 (ethyl-d5) | Sildenafil D3 | N-desmethyl Sildenafil D8 |