Ezetimibe-D4 Phenoxy Glucuronide
| Product Name | Ezetimibe-D4 Phenoxy Glucuronide |
|---|---|
| Alternate Names | Ezetimibe Stable Isotopes, Stable Isotopes of Ezetimibe |
| CAT No. | CS-O-41567 |
| CAS No. | 190448-57-8 (Unlabeled) |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 589.57 g/mol |
| Mol. For. | C30H25D4F2NO9 |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Ezetimibe |
| Canonical Smiles | C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)O)OC5C(C(C(C(O5)C(=O)O)O)O)O |
| InchIKey | UOFYCFMTERCNEW-ADEYADIWSA-N |
| Inchl | InChI=1S/C30H29F2NO9/c31-17-5-1-15(2-6-17)22(34)14-13-21-23(33(28(21)38)19-9-7-18(32)8-10-19)16-3-11-20(12-4-16)41-30-26(37)24(35)25(36)27(42-30)29(39)40/h1-12,21-27,30,34-37H,13-14H2,(H,39,40)/t21-,22+,23-,24+,25+,26-,27+,30-/m1/s1 |
| IUPAC | (2S,3S,4S,5R,6S)-6-[4-[(2S,3R)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl]phenoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Ezetimibe-D4 Phenoxy Glucuronide is a stable labeled derivative of Ezetimibe, a drug used to lower cholesterol levels in the body. It is used as an internal standard in analytical methods such as liquid chromatography-mass spectrometry (LC-MS) or gas chromatography-mass spectrometry (GC-MS) for the analysis of Ezetimibe in biological samples. Phenoxy Glucuronide is a metabolite of Ezetimibe that is formed in the liver and excreted in the urine. The addition of deuterium atoms in Ezetimibe-D4 Phenoxy Glucuronide enhances its stability and improves its detection in biological samples.
Ezetimibe works by inhibiting the absorption of cholesterol from the small intestine, thereby reducing the amount of cholesterol that enters the bloodstream. It is commonly used in the treatment of hypercholesterolemia and familial hypercholesterolemia, a genetic disorder that causes high levels of cholesterol in the blood. Ezetimibe-D4 Phenoxy Glucuronide is a useful tool in pharmacokinetic and pharmacodynamic studies of Ezetimibe, as it can help researchers to understand the metabolism and elimination of the drug in the body.
In conclusion, Ezetimibe-D4 Phenoxy Glucuronide is a valuable research tool that can aid in the analysis of Ezetimibe in biological samples. Its stable isotope labeling and specificity make it a useful internal standard in LC-MS and GC-MS analysis. Additionally, its usage can aid in the understanding of the pharmacokinetics and pharmacodynamics of Ezetimibe in the body.
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Related Compounds
Ezetimibe D4 | Ezetimibe 13C6 | Ezetimibe-d4 Diacetate | Ezetimibe N-Phenyl-D4 Phenoxy Glucuronide | Ezetimibe Hydroxy-d4 β-D-Glucuronide | Rac Ezetimibe D4 | Ezetimibe D4 (4-Fluorophenyl-2,3,5,6-d4) |