N-nitroso-desmethyl-imipramine

3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methyl-N-nitrosopropan-1-amine is a chemical compound that belongs to the class of tricyclic antidepressants. Its chemical formula is C21H25N3O2 and its molecular weight is 351.44 g/mol. It is commonly known as Nomifensine and is used to treat depression, anxiety, and other mood disorders. Nomifensine works by inhibiting the reuptake of neurotransmitters such as serotonin and norepinephrine in the brain. This leads to an increase in their concentration and helps to improve mood and reduce symptoms of depression. The chemical structure of Nomifensine includes a nitroso group, which is responsible for its ability to inhibit neurotransmitter reuptake. This group also makes it a potent nitrosating agent, which means that it can react with other molecules to form nitrosamines. Nomifensine has been found to have some potential for abuse and addiction, which has led to its withdrawal from the market in many countries. It has also been associated with some serious side effects, including liver toxicity and cardiovascular problems. In conclusion, Nomifensine is a tricyclic antidepressant that works by inhibiting neurotransmitter reuptake in the brain. Its chemical structure includes a nitroso group, which makes it a potent nitrosating agent. While it has been used to treat mood disorders, it also has the potential for abuse and serious side effects.