17α-Estradiol-D3

17α-Estradiol-D3 is a synthetic isotope-labeled version of 17α-estradiol, a naturally occurring estrogen hormone. The "D3" in the name refers to the three deuterium atoms that have been substituted for three hydrogen atoms in the molecule. This labeling allows for easier detection and quantification in biological samples. 17α-Estradiol-D3 is commonly used in biological research to study estrogen receptor activity, as well as to measure the levels of endogenous 17α-estradiol in biological fluids such as blood and urine. It is also used in clinical settings for diagnostic purposes, such as the detection of ovarian tumors. In terms of chemical structure, 17α-estradiol-D3 is a steroid hormone that is similar in structure to other estrogens such as estradiol and estriol. It interacts with estrogen receptors in the body, leading to a variety of physiological effects such as regulation of the menstrual cycle, maintenance of bone density, and promotion of breast tissue development. It is important to note that 17α-estradiol-D3 is a potent endocrine disruptor, meaning it can interfere with the normal function of the endocrine system if present in high enough concentrations. As such, it is important to handle and dispose of this compound with caution.