(R)-Remdesivir-d5

(R)-Remdesivir-d5 is a deuterated form of the antiviral drug Remdesivir, which has been used to treat COVID-19 patients. Remdesivir-d5 contains five deuterium atoms in its molecular structure, which is a heavier isotope of hydrogen. The use of deuterium in drug development is becoming more common, as it can increase drug stability, improve pharmacokinetics and reduce toxicity. (R)-Remdesivir-d5 is administered intravenously to COVID-19 patients in hospital settings. It works by inhibiting viral replication by interfering with the virus's RNA polymerase enzyme. The deuterium substitution in Remdesivir-d5 is expected to extend the half-life of the drug in the body, which could potentially reduce the frequency of dosing and improve patient outcomes. The chemical information of (R)-Remdesivir-d5 includes its molecular formula, which is C27H35N6O8P, and its molecular weight, which is 615.6 g/mol. The drug is a white to off-white powder that is soluble in water and ethanol. It has a melting point of approximately 187-189°C. Overall, (R)-Remdesivir-d5 is a promising treatment option for COVID-19 patients, and its deuterium substitution could lead to improved drug efficacy and patient outcomes. Its chemical properties and mechanism of action make it a valuable addition to the arsenal of drugs used to combat the current global pandemic.