Chemical Name |
Avanafil-13C d5 |
Alternate Names |
Avanafil Stable Isotopes, Stable Isotopes of Avanafil |
CAT No. |
CS-O-44807
|
CAS Registry# |
Not Available |
Category |
Stable Isotopes |
Stock |
Enquire
|
Mol. Wt. |
489.97 g/mol |
Mol. For. |
C2213CH21D5ClN7O3
|
Hazardous |
This is not a Hazardous Compound
|
COA |
View Sample COA
|
MSDS |
View Sample MSDS
|
Parent API |
Avanafil |
Controlled |
No |
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Return |
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Avanafil-13C d5 is a labeled version of Avanafil, a medication used to treat erectile dysfunction. This specific version of Avanafil contains five carbon-13 isotopes, which can be used for scientific research purposes such as drug metabolism studies.
Avanafil-13C d5 works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which is responsible for breaking down cyclic guanosine monophosphate (cGMP) in the smooth muscle of the penis. By blocking this enzyme, Avanafil-13C d5 increases the levels of cGMP, which leads to relaxation of the smooth muscle and increased blood flow to the penis, resulting in an erection.
The chemical formula for Avanafil-13C d5 is C23H19D5ClN6O3S, with a molecular weight of 525.03 g/mol. It is a white to off-white crystalline powder, and its solubility in water is approximately 0.04 mg/mL at 25°C.
Avanafil-13C d5 is typically administered orally in tablet form, with a recommended dosage of 100mg taken approximately 30 minutes before sexual activity. The effects of Avanafil-13C d5 typically last for around 4-5 hours.
It is important to note that Avanafil-13C d5 should not be taken by individuals who are taking nitrates for chest pain or other heart conditions, as it can cause a sudden and dangerous drop in blood pressure. It should also not be taken by individuals with severe liver or kidney disease.