N-Desmethyl N-Nitroso Tamoxifen-D3
Also known as: Tamoxifen Nitrosamine Impurities or nitrosamine impurities of Tamoxifen| Product Name | N-Desmethyl N-Nitroso Tamoxifen-D3 |
|---|---|
| Alternate Names | Tamoxifen Stable Isotopes, Stable Isotopes of Tamoxifen |
| CAT No. | CS-O-44821 |
| CAS No. | Not Available |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 389.50 g/mol |
| Mol. For. | C₂₅H₂₃D₃N₂O₂ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Tamoxifen |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
N-Desmethyl N-Nitroso Tamoxifen-D3, or NDNT-D3, is a labeled analog of N-Desmethyl N-Nitroso Tamoxifen (NDNT), which is an active metabolite of Tamoxifen, a widely used drug for the treatment of breast cancer. NDNT-D3 is used in pharmacological research to investigate the metabolism and pharmacokinetics of Tamoxifen and its derivatives.
NDNT-D3 is a nitrosamine compound, which contains a nitroso group (-NO) and an amino group (-NH2) in its chemical structure. NDNT-D3 has a molecular formula of C25H24D3N5O3, with a molecular weight of 465.53 g/mol. NDNT-D3 is a stable and non-toxic compound, and its deuterium-labeled structure allows for accurate analysis and quantification in biological samples using mass spectrometry.
NDNT-D3 is used in pharmacological research to investigate the metabolism and pharmacokinetics of Tamoxifen and its derivatives. Tamoxifen is metabolized in the liver to NDNT by cytochrome P450 enzymes. NDNT-D3 can be used as an internal standard in LC-MS/MS assays to quantify NDNT and other Tamoxifen metabolites in biological samples. The use of NDNT-D3 in pharmacological research can help to improve the understanding of the pharmacokinetics and metabolism of Tamoxifen and its impact on breast cancer treatment.
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Related Compounds
Tamoxifen 13C6 | Tamoxifen-13C6 | N-Desmethyl-4-hydroxy Tamoxifen-d5 β-D-Glucuronide (E/Z Mixture) | Tamoxifen-d3 | N-Desmethyl Tamoxifen-d5 | Tamoxifen-D5 | N-Desmethyl-4-hydroxy Tamoxifen-d5 (1:1 E/Z Mixture) |