4-Iodohippuric acid-D4

4-Iodohippuric acid-D4 is a deuterated derivative of 4-Iodohippuric acid, which is a radiographic contrast agent commonly used in renal function testing. It is a stable isotopic labeled compound that is used in medical research as an internal standard for the quantification of 4-Iodohippuric acid in biological samples. The chemical formula of 4-Iodohippuric acid-D4 is C9D4H8INO3, and its molecular weight is 266.1 g/mol. It is a white to off-white crystalline powder with a melting point of 148-150°C. The compound is soluble in water, methanol, and ethanol. In medical research, 4-Iodohippuric acid-D4 is used in conjunction with liquid chromatography-tandem mass spectrometry (LC-MS/MS) techniques to quantitatively measure the renal clearance of 4-Iodohippuric acid. This allows for the assessment of renal function in patients with renal impairment or disease. The usage of 4-Iodohippuric acid-D4 requires caution as it is a radiographic contrast agent, and its use can cause adverse effects such as allergic reactions, nausea, and vomiting. It is important to follow proper safety protocols when handling this compound, including wearing appropriate personal protective equipment and disposing of any unused compound properly. In conclusion, 4-Iodohippuric acid-D4 is a useful compound in medical research, particularly in the assessment of renal function. Its stable isotopic labeling allows for accurate quantification of 4-Iodohippuric acid and provides valuable information for the diagnosis and treatment of renal diseases.