(R)-Carvedilol-D3

(R)-Carvedilol-D3, also known as (R)-2-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]propan-1-ol-D3, is a deuterated form of the beta-blocker drug Carvedilol. This compound is used for the treatment of hypertension, heart failure, and angina. It works by blocking the effects of adrenaline on the heart and blood vessels, which reduces blood pressure and improves blood flow to the heart. The deuterium substitution in (R)-Carvedilol-D3 is a common technique used in pharmacological research to create stable isotope-labeled compounds for use in drug metabolism studies. This technique allows researchers to track the fate of the drug in the body and the extent to which it is metabolized. The chemical formula of (R)-Carvedilol-D3 is C24H24D3N2O4, and it has a molecular weight of 421.54 g/mol. Its chemical structure is similar to that of Carvedilol, with the addition of three deuterium atoms. (R)-Carvedilol-D3 is typically administered orally in tablet form. The recommended dosage varies depending on the patient's condition and response to treatment. Common side effects of (R)-Carvedilol-D3 include dizziness, fatigue, and low blood pressure. It is important to follow the prescribing doctor's instructions carefully and to report any concerning side effects. In conclusion, (R)-Carvedilol-D3 is a deuterated form of the beta-blocker drug Carvedilol, which is used to treat hypertension, heart failure, and angina. Its chemical structure is similar to that of Carvedilol, but with the addition of three deuterium atoms. (R)-Carvedilol-D3 is commonly used in pharmacological research to track the fate of the drug in the body.