Desmethoxy N-Nitroso Esomeprazol impurity

Desmethoxy N-Nitroso Esomeprazol is an impurity that is commonly found in Esomeprazole, which is a proton pump inhibitor. This impurity is formed during the manufacturing process of Esomeprazole and is a potential human carcinogen. The presence of Desmethoxy N-Nitroso Esomeprazol in Esomeprazole is strictly regulated by international pharmaceutical agencies, and its levels are required to be kept below certain limits. The usage of Desmethoxy N-Nitroso Esomeprazol impurity is primarily as a reference standard for analytical testing. It is used to identify and quantify the levels of the impurity in pharmaceutical products and to ensure that they are within acceptable limits. The impurity is also used as a starting material in the synthesis of other chemicals. From a chemical perspective, Desmethoxy N-Nitroso Esomeprazol is a nitrosamine derivative that is formed through the reaction of Esomeprazole with nitrous acid. The impurity is highly reactive and can cause DNA damage, which can lead to cancer. Therefore, it is important to monitor its levels in pharmaceutical products to ensure patient safety. In conclusion, Desmethoxy N-Nitroso Esomeprazol impurity is a potential human carcinogen that is strictly regulated in pharmaceutical products. Its usage is primarily as a reference standard for analytical testing purposes, and its chemical properties make it important to monitor its levels in pharmaceutical products.