[5',5''-D2]adenosine

[5',5''-D2]adenosine is a stable isotope-labeled form of adenosine, a purine nucleoside that plays a critical role in various physiological processes such as energy metabolism, DNA synthesis, and cellular signaling. The stable isotope labeling of adenosine involves the substitution of two deuterium atoms at the 5' and 5'' positions of the ribose sugar moiety of the nucleoside, resulting in [5',5''-D2]adenosine. The use of stable isotope-labeled compounds like [5',5''-D2]adenosine is becoming increasingly popular in biochemical and biomedical research. These labeled compounds are used as tracers or probes to study metabolic pathways, protein-ligand interactions, and drug metabolism in vivo and in vitro. [5',5''-D2]adenosine, for instance, can be used in studies that investigate adenosine metabolism and turnover in tissues and organs. It can also be used in pharmacokinetic studies to determine the absorption, distribution, metabolism, and excretion of drugs that interact with adenosine receptors. From a chemical perspective, [5',5''-D2]adenosine is a white crystalline powder that is soluble in water and ethanol. It has a molecular formula of C10H12D2N5O4 and a molecular weight of 274.25 g/mol. It is stable under normal conditions of use and storage, but may decompose under extreme heat or light. [5',5''-D2]adenosine is commercially available from various chemical suppliers and can be used in a range of biochemical and biomedical applications.