[2'-D]adenosine

2'-D-Adenosine is a modified form of adenosine, one of the four nucleosides that make up DNA. In 2'-D-Adenosine, the hydroxyl group at the 2' position of the ribose sugar has been replaced with a deuterium atom. This modification makes the molecule more stable and resistant to degradation by enzymes, making it useful for various research applications. One of the most common uses of 2'-D-Adenosine is in studies of RNA structure and function. RNA molecules contain adenosine residues, and by replacing these with 2'-D-Adenosine, researchers can investigate how the modification affects the structure and activity of the RNA. Additionally, 2'-D-Adenosine can be incorporated into RNA molecules that are being used as therapeutic agents, to enhance their stability and efficacy. In terms of safety, 2'-D-Adenosine has been shown to have low toxicity and is generally well-tolerated in animals and humans. However, as with any research chemical, caution should be exercised when handling and using the compound. Overall, 2'-D-Adenosine is a valuable tool for researchers studying RNA structure and function, and has potential applications in the development of RNA-based therapeutics.